Results 71 to 80 of about 4,123,279 (296)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Manager-Analyst Engagement and Stock Return Synchronicity [PDF]

open access: yes
Research has shown that the market actively interprets information conveyed in question and answer (Q&A) conversations during conference calls. However, previous studies have not clearly indicated how this information influences the market.
Chen, Minjia   +3 more
core   +1 more source

Self-oriented, other-oriented, and socially prescribed perfectionism in employees: Relationships with burnout and engagement [PDF]

open access: yes, 2010
Burnout and engagement impact employees, organizations, and customers in numerous positive and negative ways. Consequently, it is important to know how individual differences contribute to employees‘ burnout and engagement. The present study examined how
Stoeber, Joachim   +3 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Democratic Engagement Action Plan: 2022 Midterm Elections [PDF]

open access: yes, 2022
Illinois State University\u27s Voter Engagement Coalition is committed to a collaborative, campus wide voter engagement plan to maximize student participation in the 2022 election.https://ir.library.illinoisstate.edu/prcce/1003/thumbnail ...
Center for Civic Engagement,
core   +1 more source

Welcome to the Volume [PDF]

open access: yes, 2017
Welcome to the fifth volume of the International Journal of Research on Service-Learning and Community Engagement (IJRSLCE), the annual, online, peer-reviewed publication of the International Association for Research on Service-Learning and Community ...
Richard, Dan, Perry, Lane
core  

Assessing public engagement with science in a university primate research centre in a national zoo [PDF]

open access: yes, 2012
Recent years have seen increasing encouragement by research institutions and funding bodies for scientists to actively engage with the public, who ultimately finance their work.
Mark T Bowler   +12 more
core   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Civic Engagement Inventory

open access: yes, 2001
University of Minnesota: Office for Public Engagement. (2001). Civic Engagement Inventory.
University of Minnesota: Office for Public Engagement
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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