Results 71 to 80 of about 4,123,279 (296)
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Manager-Analyst Engagement and Stock Return Synchronicity [PDF]
Research has shown that the market actively interprets information conveyed in question and answer (Q&A) conversations during conference calls. However, previous studies have not clearly indicated how this information influences the market.
Chen, Minjia +3 more
core +1 more source
Self-oriented, other-oriented, and socially prescribed perfectionism in employees: Relationships with burnout and engagement [PDF]
Burnout and engagement impact employees, organizations, and customers in numerous positive and negative ways. Consequently, it is important to know how individual differences contribute to employees‘ burnout and engagement. The present study examined how
Stoeber, Joachim +3 more
core +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Democratic Engagement Action Plan: 2022 Midterm Elections [PDF]
Illinois State University\u27s Voter Engagement Coalition is committed to a collaborative, campus wide voter engagement plan to maximize student participation in the 2022 election.https://ir.library.illinoisstate.edu/prcce/1003/thumbnail ...
Center for Civic Engagement,
core +1 more source
Welcome to the fifth volume of the International Journal of Research on Service-Learning and Community Engagement (IJRSLCE), the annual, online, peer-reviewed publication of the International Association for Research on Service-Learning and Community ...
Richard, Dan, Perry, Lane
core
Assessing public engagement with science in a university primate research centre in a national zoo [PDF]
Recent years have seen increasing encouragement by research institutions and funding bodies for scientists to actively engage with the public, who ultimately finance their work.
Mark T Bowler +12 more
core +2 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
University of Minnesota: Office for Public Engagement. (2001). Civic Engagement Inventory.
University of Minnesota: Office for Public Engagement
core
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source

