Results 1 to 10 of about 2,773,447 (117)
Molecules, 2022 The urotensin receptor (UT receptor), a G-protein-coupled receptor mediating urotensin-II and urotensin-II-related peptide signaling in the urotensinergic system, has multiple pharmacological activities.
Na Li +9 more
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Recent advances in epigenetic anticancer therapeutics and future perspectives
Frontiers in Genetics, 2023 Tumor development is frequently accompanied by abnormal expression of multiple genomic genes, which can be broadly viewed as decreased expression of tumor suppressor genes and upregulated expression of oncogenes.
Liwen Ren +17 more
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The biology, function, and applications of exosomes in cancer
Acta Pharmaceutica Sinica B, 2021 Exosomes are cell-derived nanovesicles with diameters from 30 to 150 nm, released upon fusion of multivesicular bodies with the cell surface. They can transport nucleic acids, proteins, and lipids for intercellular communication and activate signaling ...
Jinyi Liu +9 more
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Structural optimization of static power control programs of nuclear power plants with WWER-1000
Trudy Odesskogo Politehničeskogo Universiteta, 2015 The question of possibility the power control programs switching for WWER-1000 is considered. Aim: The aim of this research is to determine the best program for the power control of nuclear reactor under cyclic diurnal behavior of electrical generation ...
E.O. Kokol
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Biology of Sex Differences, 2020 Fibroblast growth factors (FGFs) belong to a large family comprising 22 FGF polypeptides that are widely expressed in tissues. Most of the FGFs can be secreted and involved in the regulation of skeletal muscle function and structure. However, the role of
Wei-hua Jia +9 more
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Pharmacological Research, 2022 Lung cancer is by far the leading cause of cancer death worldwide, and 85% of patients are diagnosed with non-small cell lung cancer (NSCLC), which is still very difficult to treat.
Jinyi Liu +10 more
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Scientific Reports, 2021 Endoplasmic reticulum (ER) stress is a cellular state that results from the overload of unfolded/misfolded protein in the ER that, if not resolved properly, can lead to cell death.
Zijing Wang +11 more
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Frontiers in Pharmacology, 2023 Aberrant mitophagy has been identified as a driver for energy metabolism disorder in most cardiac pathological processes. However, finding effective targeted agents and uncovering their precise modulatory mechanisms remain unconquered.
Ji-Chao Zhou +20 more
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Comprehensive Lipidome Profiling of the Kidney in Early-Stage Diabetic Nephropathy
Frontiers in Endocrinology, 2020 Metabolic changes associated with diabetes are reported to lead to the onset of early-stage diabetic nephropathy (DN). Furthermore, lipotoxicity is implicated in renal dysfunction.
Biyu Hou +10 more
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Crosstalk between ferroptosis and stress—Implications in cancer therapeutic responses
Cancer Innovation, 2022 Ferroptosis is a newly discovered form of cell death that is characterized by the accumulation of iron‐dependent lipid peroxidation. Research on ferroptosis has seen exponential growth over the past few years.
Cheng Zhang +6 more
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