Results 111 to 120 of about 927,175 (307)

Tutoring electronic troubleshooting in a simulated maintenance work environment [PDF]

A series of intelligent tutoring systems, or intelligent maintenance simulators, is being developed based on expert and novice problem solving data. A graded series of authentic troubleshooting problems provides the curriculum, and adaptive instructional
Gott, Sherrie P.
core   +1 more source

The use of the task-based instruction in the development of lexical compentence [PDF]

, 2016
Este proyecto tiene como finalidad mostrar cómo se aplicó la teórica del Task-Based Instruction (TBI) para desarrollar la competencia lexical, basadas en actividades guiadas dentro del aula de clases.
Balanta Leudo, Jennfer Lorena, Morales Rojas, Duber Aleicer, Torres Molina, Maryeleth Tatiana   +2 more
core  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Task-based Performance Assessment for Teachers: Key Issues to Consider

Studies in Applied Linguistics & TESOL, 2004
In the last two decades or so, the tenets of communicative language teaching with their strong emphasis on students’ ability to use language in real-life situations have taken hold in foreign and second language classrooms.
Hyunjoo Kim
doaj   +1 more source

Superintendents and Professional Development: Voices from the Field [PDF]

, 2018
The primary task of the educational leader is to assure high quality learning environments for all students. Research (Gordon, 2004; Sparks, 2007) supports the proposition that effective professional development contributes to instructional improvement ...
Aguilar, Israel, Boone, Mike, Edwards, Dessynie, Nino, Juan M.   +3 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Impact of Task-based and Task-supported L2 Teaching on the Use of Connective Markers in Learners’ Written Performance

Theory and Practice of Second Language Acquisition
The current study investigates the impact of two types of instruction on teaching connective markers in learners' written performance. 82 EFL learners were assigned to two experimental groups (EG1, N = 29 and EG2, N = 25) and one control group (CG, N ...
Tomasz Róg, Artur Urbaniak
doaj   +1 more source

Interactively Picking Real-World Objects with Unconstrained Spoken Language Instructions

, 2018
Comprehension of spoken natural language is an essential component for robots to communicate with human effectively. However, handling unconstrained spoken instructions is challenging due to (1) complex structures including a wide variety of expressions ...
Hatori, Jun, Kikuchi, Yuta, Ko, Wilson, Kobayashi, Sosuke, Takahashi, Kuniyuki, Tan, Jethro, Tsuboi, Yuta, Unno, Yuya   +7 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

PENERAPAN MODEL PBI (PROBLEM BASED INSTRUCTION) BERORIENTASI LINGKUNGAN UNTUK MENINGKATKAN HASIL BELAJAR SISWA PADA KONSEP LINGKUNGAN DI KELAS X-3 SMA NEGERI 1 MANDIRANCAN KABUPATEN KUNINGAN (Penelitian Tindakan Kelas) [PDF]

, 2013
Penelitian ini dilatar belakangi oleh keresahan guru dalam hal ini merasakan adanya kesenjangan antara harapan guru dengan keadaan siswa dalam proses pembelajaran di kelas, yang berpengaruh terhadap pencapaian tujuan dan hasil pembelajaran ...
RUSLI HAMZAH,
core