Results 91 to 100 of about 188,887 (312)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

The Effects of Task-Based Instruction on Vietnamese EFL Learners’ Speech Production Capacity [PDF]

open access: yes, 2021
This study investigates the effects of task-based instruction on EFL learners’ speech production. The study employed an experimental pre-test/post-test design with the participation of 102 Vietnamese EFL learners who were randomly assigned to two task ...
Do, Thi Huyen Thanh
core  

The impact of task-based and task-supported instruction on the acquisition of L2 hedge phrases

open access: yesModerna Språk
Despite a growing interest in task-based teaching in second language acquisition research and L2 instruction, classroom-based studies investigating its applicability to L2 pragmatics instruction remain scarce.
Tomasz Róg
doaj   +1 more source

Implementing The Task-based Learning Approach In Teaching Linguistics To First Year University Students

open access: yesAl-Lisaniyyat, 2015
Communicative language teaching has given birth to a number of approaches that share the same basic principles, but which spell out different instructional principles. These approaches include Content-Based Instruction (CBI) and Task-Based Learning (TBL).
Nesrine Aoudjit Bessai
doaj   +1 more source

Online Instruction Based on Task-based Language Teaching

open access: yesStudies in Linguistics and Literature, 2021
The outbreak of the COVID-19 caused many Chinese universities to initiate online teaching. This paper aimed to develop Task-based Language Teaching (TBLT) practices in online courses to enable teachers and students in China to employ TBLT appropriately and effectively.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Orienting to pedagogical innovation: A case study of Vietnamese teachers' beliefs and practices regarding Task-based Language Teaching [PDF]

open access: yes, 2013
Although research into language teacher cognition has become a well-established domain of inquiry for applied linguists over the past few decades, few in-depth studies have explored language teachers’ beliefs regarding task-based language teaching (TBLT).
Nguyen, Gia Viet
core  

The Effect of WeChat-Based Instruction on Chinese EFL Undergraduates’ Business English Writing Performance [PDF]

open access: yes, 2023
With the vigorous development of the Internet, the continuous application of social media platforms has accelerated people's channels to obtain information.
Asmawi , Adelina, Sun , Lixuan
core  

Compatible bedfellows: Enriching grammar pedagogical tasks with cognitive linguistics to teach present simple vs. progressive [PDF]

open access: yesنشریه پژوهش‌های زبان‌شناسی
While many English language learning textbooks provide exercises on the difference between present simple and present progressive tenses, they often lack meticulous explanations regarding their meaning and contextual usage.
Mojtaba Maghsoudi, Abolfazl Khodamoradi
doaj   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

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