Results 81 to 90 of about 927,175 (307)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

The effects of different types of video modelling on undergraduate students’ motivation and learning in an academic writing course

Journal of Writing Research, 2017
This study extends previous research on observational learning in writing. It was our objective to enhance students’ motivation and learning in an academic writing course on research synthesis writing.
Mariet Raedts , Elke Van Steendam, Luc De Grez, Jef Hendrickx, Chris Masui   +4 more
doaj   +1 more source

Temporal Stimulus Generalization in Humans [PDF]

, 2014
Two experiments investigated temporal generalization in humans using a computer based task which presented red dots with a range of lines at different angles and durations.
Hay, Louise
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Implementing The Task-based Learning Approach In Teaching Linguistics To First Year University Students

Al-Lisaniyyat, 2015
Communicative language teaching has given birth to a number of approaches that share the same basic principles, but which spell out different instructional principles. These approaches include Content-Based Instruction (CBI) and Task-Based Learning (TBL).
Nesrine Aoudjit Bessai
doaj   +1 more source

Mindful Eating: Trait and State Mindfulness Predict Healthier Eating Behavior

, 2014
Obesity and excess weight are significant societal problems. Mindfulness may encourage healthier weight and eating habits. Across four studies, we found a positive relation between mindfulness and healthier eating.
Donatoni, Linda R., Jordan, Christian H., Meier, Brian P., Wang, Wan   +3 more
core   +2 more sources

The Securities and Exchange Commission and Accounting Principles [PDF]

, 1965
In this thesis we address the problem of optimal code generation for irregular architectures such as Digital Signal Processors (DSPs). Code generation consists mainly of three interrelated optimization tasks: instruction selection (with resource ...
Pines, J. Arnold
core   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

The impact of task-based and task-supported instruction on the acquisition of L2 hedge phrases

Moderna Språk
Despite a growing interest in task-based teaching in second language acquisition research and L2 instruction, classroom-based studies investigating its applicability to L2 pragmatics instruction remain scarce.
Tomasz Róg
doaj   +1 more source

Compatible bedfellows: Enriching grammar pedagogical tasks with cognitive linguistics to teach present simple vs. progressive [PDF]

نشریه پژوهش‌های زبان‌شناسی
While many English language learning textbooks provide exercises on the difference between present simple and present progressive tenses, they often lack meticulous explanations regarding their meaning and contextual usage.
Mojtaba Maghsoudi, Abolfazl Khodamoradi
doaj   +1 more source