Results 61 to 70 of about 188,887 (312)
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Integrating multiple individual differences in web-based instruction [PDF]
, 2014 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.There has been an increasing focus on web-based instruction (WBI) systems which accommodate individual differences in educational environments.
Alhajri, Rana Ali
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Process versus product? : personal reflection and experimentation in task-based learning with the Hiroshima Teacher Trainees 2008 [PDF]
, 2008 In my ten years of teaching, I’ve spent a considerable amount of time devising the best ways to teach linguistic elements, such as grammar or pronunciation targets.
Searle, Clari
core
IEEE AccessManual assembly is critical in manufacturing, but it is susceptible to human errors, influenced by task complexity, the clarity of work instructions, and the physical demands on the operator.
Mohammed A. Noman +5 more
doaj +1 more source
Cache WCET Analysis Method with Instruction Prefetching on Multi-cores [PDF]
Jisuanji gongcheng, 2018 In order to ensure Hard Real-time Task(HRT) to meet deadlines,their Worst Case Execution Time(WCET) with instruction prefetching need to be analyzed.Although the cache analysis methods with instruction prefetching in single-core have already existed,the ...
AN Likui,HAN Liyan
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
AmpersandThe study compares the effectiveness of two communicative approaches to grammar teaching, Processing Instruction (PI) and Production-Based instruction with collaborative tasks (PB), on the acquisition of past tense verb morphology by child heritage ...
Panagiota-Aikaterini Ouli, Irini Konta
doaj +1 more source
Characterizing task-based OpenMP programs. [PDF]
PLoS ONE, 2015 Programmers struggle to understand performance of task-based OpenMP programs since profiling tools only report thread-based performance. Performance tuning also requires task-based performance in order to balance per-task memory hierarchy utilization ...
Ananya Muddukrishna +2 more
doaj +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source