Results 51 to 60 of about 23,906,714 (250)

Personalizing the design of computer‐based instruction to enhance learning [PDF]

, 1998
This paper reports two studies designed to investigate the effect on learning outcomes of matching individuals’ preferred cognitive styles to computer‐based instructional (CBI) material.
Hitendra Pillay, Boles, Wageeh W., Leonard Raj, Pillay, Hitendra, Boles, Wageeh, Wageeh Boles, Raj, Leonard, Pillay, Hitendra K.   +7 more
core   +2 more sources

An Emerging Theory for Evidence Based Information Literacy Instruction in School Libraries, Part 1: Building a Foundation

Evidence Based Library and Information Practice, 2009
Objective – Part I of this paper aims to create a framework for an emerging theory of evidence based information literacy instruction. In order to ground this framework in existing theory, a holistic perspective views inquiry as a learning process that ...
Carol A. Gordon
doaj   +3 more sources

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Intelligibility, comprehensibility, and accentedness in L2 speech: Effects of explicit pronunciation instruction and task-supported language teaching

Canadian Journal of Applied Linguistics
While explicit instruction helps L2 learners in pronunciation learning (Lee et al., 2015; Saito & Plonsky, 2019), task-based language teaching enhances second language (L2) pronunciation development when learners are exposed to tasks that vary in ...
Joshua Gordon
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

The effectiveness of processing instruction and production-based instruction on the acquisition of the past tense in Greek by child heritage learners: A preliminary study

Ampersand
The study compares the effectiveness of two communicative approaches to grammar teaching, Processing Instruction (PI) and Production-Based instruction with collaborative tasks (PB), on the acquisition of past tense verb morphology by child heritage ...
Panagiota-Aikaterini Ouli, Irini Konta
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Impact of Instruction Methods and Task Size on Human Performance and Physical Workload in Manual Assembly

IEEE Access
Manual assembly is critical in manufacturing, but it is susceptible to human errors, influenced by task complexity, the clarity of work instructions, and the physical demands on the operator.
Mohammed A. Noman, Fahad M. Alqahtani, Wadea Ameen, Mohammed H. Alhaag, Adeeb A. Ahmed, Abdelaty E. Abdelgawad   +5 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source