Results 51 to 60 of about 188,887 (312)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Task complexity, focus on L2 constructions, and individual differences : a classroom-based study. [PDF]

open access: yes, 2011
Motivated by cognitive-interactionist frameworks for task-based learning, this study explored whether task complexity affects the extent to which learners focus on form-meaning connections during task-based work in a classroom setting, and whether this ...
Révész, Andrea
core  

Delving into Secondary School EFL Teachers’ Practices Facilitated by Task-Based Language Instruction

open access: yesSEEU Review
The implementation of Task-Based Instruction (TBI) has resulted in a productive transformation for many foreign language teachers, since it emphasizes the importance of context and meaningful language use.
Syla Rrita
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

An Emerging Theory for Evidence Based Information Literacy Instruction in School Libraries, Part 1: Building a Foundation

open access: yesEvidence Based Library and Information Practice, 2009
Objective – Part I of this paper aims to create a framework for an emerging theory of evidence based information literacy instruction. In order to ground this framework in existing theory, a holistic perspective views inquiry as a learning process that ...
Carol A. Gordon
doaj   +3 more sources

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

Report of the CLA Task Force on Foreign Language Instruction, June, 1983 [PDF]

open access: yes, 1983
University of Minnesota. College of Liberal Arts. Task Force on Foreign Language Instruction, 1983. (1983). Report of the CLA Task Force on Foreign Language Instruction, June, 1983.
University of Minnesota. College of Liberal Arts. Task Force on Foreign Language Instruction, 1983
core  

Is Task-Based Instruction Approach Apt for Journalism Education? [PDF]

open access: yesCurrent Research Journal of Social Sciences and Humanities, 2018
The university teaching and learning of Journalism and Communication in Ethiopia offers many challenges equally both for the teachers and students. One of the challenges is that the undergraduates usually face language difficulties in an English-medium setting. Task based instruction (TBI) as a panacea refers to an approach based on the use of tasks as
SHAFAAT HUSSAIN, SADAQUAT HUSSAIN
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Trayectorias: a new model for online task-based learning [PDF]

open access: yes, 2004
This paper discusses a framework for designing online tasks that capitalizes on the possibilities that the Internet and the Web offer for language learning.
Raquel Mardomingo   +3 more
core  

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