Results 111 to 120 of about 1,245,475 (338)

Introduction: Crying over Little Nell [PDF]

open access: yes, 2007
Do you ever find yourself coming over all sentimental? And if you do, do you like it, or do you feel embarrassed by your sentimental proclivities? Is sentimentality a pleasurable indulgence, a minor vice, or a lapse of aesthetic and moral taste?
Bown, Nicola
core   +2 more sources

The Representation of Umami Taste in the Taste Cortex [PDF]

open access: yesThe Journal of Nutrition, 2000
To investigate the neural encoding of glutamate (umami) taste in the primate, recordings were made from taste-responsive neurons in the cortical taste areas in macaques. Most of the neurons were in the orbitofrontal cortex (secondary) taste area. First, it was shown that there is a representation of the taste of glutamate that is separate from the ...
openaire   +2 more sources

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Differential connectivity of the posterior piriform cortex in Parkinson’s disease and postviral olfactory dysfunction: an fMRI study

open access: yesScientific Reports
Olfactory dysfunction is a common feature of both postviral upper respiratory tract infections (PV) and idiopathic Parkinson’s disease (PD). Our aim was to investigate potential differences in the connectivity of the posterior piriform cortex, a major ...
Charalampos Georgiopoulos   +5 more
doaj   +1 more source

Egalitarian justice and valuational judgment [PDF]

open access: yes, 2009
Contemporary discussions of egalitarian justice have often focused on the issue of expensive taste. G.A. Cohen has recently abandoned the view that all chosen disadvantages are non-compensable, now maintaining that chosen expensive judgmental tastes ...
Knight, C.
core   +2 more sources

Menthol‐like cooling compounds, including (R)‐(‐)‐carvone, inhibit the human bitter taste receptors for saccharin and acesulfame K

open access: yesFEBS Open Bio, EarlyView.
We report that some menthol‐like cooling compounds, including (R)‐(‐)‐carvone, act as inhibitors of TAS2R31 and TAS2R43, which are taste receptors responsible for the intrinsic bitter aftertastes of saccharin and acesulfame K. However, there was little correlation between the intensity of the cooling sensation and the potency of bitterness inhibition ...
Miyuu Saito, Takumi Misaka
wiley   +1 more source

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

Reactive microglia after taste nerve injury: comparison to nerve injury models of chronic pain [v1; ref status: indexed, http://f1000r.es/wh]

open access: yesF1000Research, 2013
The chorda tympani (CT), which innervates taste buds on the anterior portion of the tongue, is susceptible to damage during inner ear surgeries. Injury to the CT causes a disappearance of taste buds, which is concurrent with significant microglial ...
Dianna L Bartel, Thomas E Finger
doaj   +1 more source

A Taste of the Maori Culture! [PDF]

open access: yes, 2010
Postcard from Kailee Seto, during the Linfield College Semester Abroad Program at the University of Waikato in Hamilton, New ...
Seto, Kailee
core   +1 more source

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