Results 11 to 20 of about 436,774 (328)
Taste Receptors beyond Taste Buds. [PDF]
Int J Mol Sci, 2022 Taste receptors are responsible for detecting their ligands not only in taste receptor cells (TRCs) but also in non-gustatory organs. For several decades, many research groups have accumulated evidence for such “ectopic” expression of taste receptors ...
Ki SY, Jeong YT.
europepmc +4 more sources
Taste transduction and channel synapses in taste buds. [PDF]
Pflugers Arch, 2021 The variety of taste sensations, including sweet, umami, bitter, sour, and salty, arises from diverse taste cells, each of which expresses specific taste sensor molecules and associated components for downstream signal transduction cascades. Recent years
Taruno A +5 more
europepmc +4 more sources
Neurotrophins in Zebrafish Taste Buds [PDF]
Animals, 2022 The neurotrophin family is composed of nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), Neurotrophin 3 (NT3) and NT4. These neurotrophins regulate several crucial functions through the activation of two types of transmembrane ...
Claudia Gatta +4 more
doaj +5 more sources
Consequences of Obesity on the Sense of Taste: Taste Buds as Treatment Targets? [PDF]
Diabetes & Metabolism Journal, 2020 Premature obesity-related mortality is caused by cardiovascular and pulmonary diseases, type 2 diabetes mellitus, physical disabilities, osteoarthritis, and certain types of cancer.
Kerstin Rohde +2 more
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Functional Cell Types in Taste Buds Have Distinct Longevities [PDF]
PLoS ONE, 2013 Taste buds are clusters of polarized sensory cells embedded in stratified oral epithelium. In adult mammals, taste buds turn over continuously and are replenished through the birth of new cells in the basal layer of the surrounding non-sensory epithelium.
Takatoshi Nagai, Nirupa Chaudhari
exaly +3 more sources
A taste for ATP: neurotransmission in taste buds [PDF]
Frontiers in Cellular Neuroscience, 2013 Not only is ATP a ubiquitous source of energy but it is also used widely as an intercellular signal. For example, keratinocytes release ATP in response to numerous external stimuli including pressure, heat and chemical insult. The released ATP activates
Thomas E. Finger, Sue C Kinnamon
doaj +4 more sources
Expression and Secretion of TNF-α in Mouse Taste Buds: A Novel Function of a Specific Subset of Type II Taste Cells [PDF]
PLoS ONE, 2012 Taste buds are chemosensory structures widely distributed on the surface of the oral cavity and larynx. Taste cells, exposed to the oral environment, face great challenges in defense against potential pathogens.
Pu Feng, Hang Zhao, Liquan Huang
exaly +3 more sources
Taste buds: cells, signals and synapses [PDF]
Nature Reviews Neuroscience, 2017 The past decade has witnessed a consolidation and refinement of the extraordinary progress made in taste research. This Review describes recent advances in our understanding of taste receptors, taste buds, and the connections between taste buds and ...
Stephen D Roper, Nirupa Chaudhari
exaly +3 more sources
Single-cell transcriptomics uncovers the differentiation of a subset of murine esophageal progenitors into taste buds in vivo. [PDF]
Sci Adv, 2023 Mouse esophagus is lined with a stratified epithelium, which is maintained by the constant renewal of unipotent progenitors. In this study, we profiled mouse esophagus by single-cell RNA sequencing and found taste buds specifically in the cervical ...
Vercauteren Drubbel A, Beck B.
europepmc +2 more sources
Lipopolysaccharide-induced inflammation increases nitric oxide production in taste buds. [PDF]
Brain Behav Immun, 2022 Inducible nitric oxide synthase (iNOS) is expressed when cells are induced or stimulated by proinflammatory cytokines and/or bacterial lipopolysaccharide (LPS). iNOS is a downstream gene of the NF-κB pathway.
Wu Z +7 more
europepmc +2 more sources