Evolutionary origins of taste buds: phylogenetic analysis of purinergic neurotransmission in epithelial chemosensors [PDF]
Open Biology, 2013 Taste buds are gustatory endorgans which use an uncommon purinergic signalling system to transmit information to afferent gustatory nerve fibres. In mammals, ATP is a crucial neurotransmitter released by the taste cells to activate the afferent nerve ...
Masato Kirino +4 more
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Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury. [PDF]
PLoS ONE, 2013 Taste buds are composed of a variety of taste receptor cell types that develop from tongue epithelium and are regularly replenished under normal homeostatic conditions as well as after injury.
Norifumi Takeda +5 more
doaj +1 more source
METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis
International Journal of Oral Science, 2022 The dorsal lingual epithelium, which is composed of taste buds and keratinocytes differentiated from K14+ basal cells, discriminates taste compounds and maintains the epithelial barrier.
Qiuchan Xiong +10 more
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Qualitative and quantitative differences between taste buds of the rat and mouse
BMC Neuroscience, 2007 Background Numerous electrophysiological, ultrastructural, and immunocytochemical studies on rodent taste buds have been carried out on rat taste buds. In recent years, however, the mouse has become the species of choice for molecular and other studies ...
Ma Huazhi +3 more
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Fingerprinting taste buds: intermediate filaments and their implication for taste bud formation [PDF]
Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 2000 Intermediate filaments in taste organs of terrestrial (human and chick) as well as aquatic ( Xenopus laevis ) species were detected using immunohistochemistry and electron microscopy. During development, the potential importance of the interface between the taste bud primordium and non ...
M, Witt +3 more
openaire +2 more sources
Is fat the sixth taste primary? Evidence and implications [PDF]
, 2015 Explores our tongue\u27s ability to detect fat as a distinct taste similar to our ability to sense sweet, sour, bitter, acid and savory. Abstract Taste is the chemical sense responsible for the detection of non-volatile chemicals in potential foods. For
Russell Keast +2 more
core +1 more source
β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. [PDF]
PLoS Genetics, 2017 Taste stimuli are transduced by taste buds and transmitted to the brain via afferent gustatory fibers. Renewal of taste receptor cells from actively dividing progenitors is finely tuned to maintain taste sensitivity throughout life.
Dany Gaillard +5 more
doaj +1 more source
Taste buds: cells, signals and synapses. [PDF]
Nat Rev Neurosci, 2017 The past decade has witnessed a consolidation and refinement of the extraordinary progress made in taste research. This Review describes recent advances in our understanding of taste receptors, taste buds, and the connections between taste buds and ...
Roper SD, Chaudhari N.
europepmc +2 more sources
Opiate agonists and antagonists modulate taste perception in opiate-maintained, and recently detoxified subjects. [PDF]
, 2013 Heroin addicts consume large quantities of refined sugars. This study investigated the effect of opiate use and antagonism on sweet taste in opiate-maintained drug users and detoxified former chronic opiate users, using a within-subject design.
Green, Amy +14 more
core +1 more source
Taste isn't just for taste buds anymore [PDF]
F1000 Biology Reports, 2011 Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste buds) and at least two distinct families of G protein-coupled receptor molecules that detect nutritionally important substances or potential toxins. Yet the receptor mechanisms that drive taste also are utilized by numerous systems throughout the body.
Finger, Thomas E., Kinnamon, Sue C.
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