Qualitative and quantitative differences between taste buds of the rat and mouse [PDF]
BMC Neuroscience, 2007 Background Numerous electrophysiological, ultrastructural, and immunocytochemical studies on rodent taste buds have been carried out on rat taste buds. In recent years, however, the mouse has become the species of choice for molecular and other studies ...
Ma Huazhi +3 more
doaj +2 more sources
Cellular Diversity and Regeneration in Taste Buds. [PDF]
Curr Opin Physiol, 2021 Taste buds are the sensory end organs for gustation, mediating sensations of salty, sour, bitter, sweet and umami as well as other possible modalities, e.g. fat and kokumi. Understanding of the structure and function of these sensory organs has increased
Finger TE, Barlow LA.
europepmc +2 more sources
"Tripartite Synapses" in Taste Buds: A Role for Type I Glial-like Taste Cells. [PDF]
J Neurosci, 2021 In mammalian taste buds, Type I cells comprise half of all cells. These are termed “glial-like” based on morphologic and molecular features, but there are limited studies describing their function.
Rodriguez YA +5 more
europepmc +2 more sources
Suspension-cultured taste bud organoids recapitulate in vivo taste buds [PDF]
Organoid, 2023 Background Taste buds are a complex organ and require a plethora of growth factors for their development, homeostasis, and regeneration. Taste bud organoids provide a platform for understanding their development, disease and regeneration. Methods In this
Anish Ashok Adpaikar +2 more
doaj +2 more sources
Genome-Wide Analysis of Gene Expression in Primate Taste Buds Reveals Links to Diverse Processes [PDF]
PLoS ONE, 2009 Efforts to unravel the mechanisms underlying taste sensation (gustation) have largely focused on rodents. Here we present the first comprehensive characterization of gene expression in primate taste buds.
Albert Zlotnik
exaly +2 more sources
Contribution of Underlying Connective Tissue Cells to Taste Buds in Mouse Tongue and Soft Palate. [PDF]
PLoS ONE, 2016 Taste buds, the sensory organs for taste, have been described as arising solely from the surrounding epithelium, which is in distinction from other sensory receptors that are known to originate from neural precursors, i.e., neural ectoderm that includes ...
Kristin Boggs +8 more
doaj +2 more sources
Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds. [PDF]
PLoS ONE, 2016 Growth factors regulate cell growth and differentiation in many tissues. In the taste system, as yet unknown growth factors are produced by neurons to maintain taste buds.
Bradley T Biggs, Tao Tang, Robin F Krimm
doaj +2 more sources
SARS-CoV-2 Receptor ACE2 Is Enriched in a Subpopulation of Mouse Tongue Epithelial Cells in Nongustatory Papillae but Not in Taste Buds or Embryonic Oral Epithelium. [PDF]
ACS Pharmacol Transl Sci, 2020 As a result of the COVID-19 pandemic, evidence revealed that SARS-CoV-2 infection caused taste loss at a rate higher than that of influenza. ACE2, the entry receptor of SARS-CoV-2, has been identified in the oral epithelium; however, it is unclear at ...
Wang Z +5 more
europepmc +2 more sources
Evolutionary origins of taste buds: phylogenetic analysis of purinergic neurotransmission in epithelial chemosensors [PDF]
Open Biology, 2013 Taste buds are gustatory endorgans which use an uncommon purinergic signalling system to transmit information to afferent gustatory nerve fibres. In mammals, ATP is a crucial neurotransmitter released by the taste cells to activate the afferent nerve ...
Masato Kirino +4 more
doaj +2 more sources
Neural Regeneration Research, 2015 The morphological changes that occur in the taste buds after denervation are not well understood in rats, especially in the contralateral tongue epithelium.
Yi-ke Li +4 more
doaj +2 more sources