Results 31 to 40 of about 52,730 (339)
METTL3-mediated m6A RNA methylation regulates dorsal lingual epithelium homeostasis
International Journal of Oral Science, 2022 The dorsal lingual epithelium, which is composed of taste buds and keratinocytes differentiated from K14+ basal cells, discriminates taste compounds and maintains the epithelial barrier.
Qiuchan Xiong +10 more
doaj +1 more source
β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. [PDF]
PLoS Genetics, 2017 Taste stimuli are transduced by taste buds and transmitted to the brain via afferent gustatory fibers. Renewal of taste receptor cells from actively dividing progenitors is finely tuned to maintain taste sensitivity throughout life.
Dany Gaillard +5 more
doaj +1 more source
Functional cell types in taste buds have distinct longevities. [PDF]
PLoS ONE, 2013 Taste buds are clusters of polarized sensory cells embedded in stratified oral epithelium. In adult mammals, taste buds turn over continuously and are replenished through the birth of new cells in the basal layer of the surrounding non-sensory epithelium.
Isabel Perea-Martinez +2 more
doaj +1 more source
Nicotine-Induced Effects on Nicotinic Acetylcholine Receptors (nAChRs), Ca2+ and Brain-Derived Neurotrophic Factor (BDNF) in STC-1 Cells [PDF]
, 2016 In addition to the T2R bitter taste receptors, neuronal nicotinic acetylcholine receptors (nAChRs) have recently been shown to be involved in the bitter taste transduction of nicotine, acetylcholine and ethanol.
Alkahtan, Reem M. +6 more
core +6 more sources
Taste isn't just for taste buds anymore [PDF]
F1000 Biology Reports, 2011 Taste is a discriminative sense involving specialized receptor cells of the oral cavity (taste buds) and at least two distinct families of G protein-coupled receptor molecules that detect nutritionally important substances or potential toxins. Yet the receptor mechanisms that drive taste also are utilized by numerous systems throughout the body.
Finger, Thomas E., Kinnamon, Sue C.
openaire +2 more sources
Insulin-Like Growth Factors Are Expressed in the Taste System, but Do Not Maintain Adult Taste Buds. [PDF]
PLoS ONE, 2016 Growth factors regulate cell growth and differentiation in many tissues. In the taste system, as yet unknown growth factors are produced by neurons to maintain taste buds.
Bradley T Biggs, Tao Tang, Robin F Krimm
doaj +1 more source
European Journal of Histochemistry, 2022 Zinc is an essential trace element, and its deficiency causes taste dysfunction. Zinc accumulates in zinc transporter (ZnT)3-expressing presynaptic vesicles in hippocampal neurons and acts as a neurotransmitter in the central nervous system.
Kentaro Nishida +5 more
doaj +1 more source
Occurrence of gustducin-immunoreactive cells in von Ebner's glands of guinea pigs [PDF]
, 2013 An immunohistochemical examination of guinea-pig taste buds in vallate papillae revealed gustducin-immunoreactive cells in the area of von Ebner’s glands, minor salivary glands.
Haga-Tsujimura, Maiko +3 more
core +1 more source
BMC Neuroscience, 2009 Background In rodents, dietary Na+ deprivation reduces gustatory responses of primary taste fibers and central taste neurons to lingual Na+ stimulation.
Stähler Frauke, Huang Tao
doaj +1 more source