Results 21 to 30 of about 6,894 (164)

The value of grip test, lysophosphatidlycholines, glycerophosphocholine, ornithine, glucuronic acid decrement in assessment of nutritional and metabolic characteristics in hepatitis B cirrhosis. [PDF]

PLoS ONE, 2017
The liver is essential for the regulation of energy, protein and amino acids, as well as in other aspects of metabolism. To identify efficient indexes for evaluation of nutritional status and metabolic characteristics during different Child-Pugh stages ...
Qing Ye, Weili Yin, Lei Zhang, Huijuan Xiao, Yumei Qi, Shuye Liu, Baoxin Qian, Fengmei Wang, Tao Han   +8 more
doaj   +1 more source

Taurine Grafted Micro-Implants Improved Functions without Direct Dependency between Interleukin-6 and the Bile Acid Lithocholic Acid in Plasma

Biomedicines, 2022
A recent study showed an association between diabetes development and the bile acid lithocholic acid (LCA), while another study demonstrated positive biological effects of the conjugated bile acid, taurocholic acid (TCA), on pancreatic cells.
Armin Mooranian, Corina Mihaela Ionescu, Susbin Raj Wagle, Bozica Kovacevic, Daniel Walker, Melissa Jones, Jacqueline Chester, Thomas Foster, Edan Johnston, Sanja Kojic, Goran Stojanovic, Momir Mikov, Hani Al-Salami   +12 more
doaj   +1 more source

Inhibition of ileal sodium-dependent bile acid transport by 2164U90.

Journal of Lipid Research, 1995
Inhibition of the ileal bile acid active transport system, previously shown to be mechanism underlying the hypocholesterolemic activity of 2164U90 in rodents, was further characterized in isolated intestinal preparations from three species.
C Root, C D Smith, D A Winegar, L E Brieaddy, M C Lewis   +4 more
doaj   +1 more source

Taurocholic acid improves hepatocyte lipid deposition by regulating macrophage polarization through TGR5

陆军军医大学学报, 2023
Objective To investigate the effect of taurocholic acid (TLCA) regulating palmitic acid (PA)-induced macrophage polarization on hepatocyte lipid metabolism.
MA Qin, MA Qin, JIANG Lincheng, JIANG Lincheng   +3 more
doaj   +1 more source

Deletion of mouse FXR gene disturbs multiple neurotransmitter systems and alters neurobehavior

Frontiers in Behavioral Neuroscience, 2015
Farnesoid X receptor (FXR) is a nuclear hormone receptor involved in bile acid synthesis and homeostasis. Dysfunction of FXR is involved in cholestasis and atherosclerosis.
Fei eHuang, Tingting eWang, Yunyi eLan, Li eYang, Weihong ePan, Yonghui eZhu, Boyang eLv, Yuting eWei, Hailian eShi, Hui eWu, Beibei eZhang, Jie eWang, Xiaofeng eDuan, Zhibi eHu, Xiaojun eWu   +14 more
doaj   +1 more source

A gut–brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus

Molecular Metabolism, 2018
Objective: Bile acids have been implicated as important regulators of glucose metabolism via activation of FXR and GPBAR1. We have previously shown that FGF19 can modulate glucose handling by suppressing the activity of hypothalamic AGRP/NPY neurons.
Shunmei Liu, Genevieve Marcelin, Clemence Blouet, Jae Hoon Jeong, Young-Hwan Jo, Gary J. Schwartz, Streamson Chua, Jr.   +6 more
doaj   +1 more source

Serum Taurocholic Acid Levels Have Predictive Value for Adverse Maternal and Infant Outcomes in Pregnant Women with Intrahepatic Cholestasis of Pregnancy: A Prospective Cohort Study

Clinical and Experimental Obstetrics & Gynecology, 2023
Background: Intrahepatic cholestasis of pregnancy (ICP) is a common liver disorder specific to pregnancy. Taurocholic acid (TCA) has been implicated in the pathogenesis of ICP.
Yan Chen, Hong Li, Huanhuan Guo, Junjie Zhou   +3 more
doaj   +1 more source

Effects of 2164U90 on ileal bile acid absorption and serum cholesterol in rats and mice.

Journal of Lipid Research, 1995
2164U90, [(3R,5R)-trans-3-butyl-3-ethyl-2,3,4,5-tetrahydro-5-phenyl-1,4- benzothiazepine 1,1-dioxide], was found to be a potent inhibitor of the ileal bile acid active transport system.
M C Lewis, L E Brieaddy, C Root
doaj   +1 more source

Circadian distribution of bile acid in the enterohepatic circulatory system in hamsters

Journal of Lipid Research, 1976
The distribution of bile acid in the enterohepatic circulatory system at different times of the day was determined in 48 hamsters exposed to a rigid light schedule (6 AM to 6 PM) and fed, ad libitum, for 4 weeks.
K J Ho
doaj   +1 more source

Protective Effects of Bile Acids Against Hepatic Lipid Accumulation in Hybrid Grouper Fed a High-Lipid Diet

Frontiers in Nutrition, 2022
Bile acids (BAs) usually display growth-promoting and lipid-lowering properties when supplemented to the diet. The effects of a high-lipid diet (HD) and BAs supplementation on growth performance and lipid deposition of hybrid grouper (Epinephelus ...
Jia Xu, Xiaoyue Li, Xinzhou Yao, Shiwei Xie, Shiwei Xie, Shiwei Xie, Shuyan Chi, Shuyan Chi, Shuyan Chi, Shuang Zhang, Shuang Zhang, Shuang Zhang, Junming Cao, Junming Cao, Junming Cao, Beiping Tan, Beiping Tan, Beiping Tan   +17 more
doaj   +1 more source