Results 91 to 100 of about 3,991 (207)
The production of taxuyunnanine C (Tc) (2 alpha, 5 alpha, 10 beta, 14 beta-tetraacetoxytaxa-4(20), 11(12)-diene) was significantly enhanced when Taxus chinensis cell cultures were treated with methyl jasmonate (MJA) or 2,3-dihydroxypropyl jasmonate ...
Xiao, Hong-Bin +3 more
core
Cancer is one of the top two leading causes of death in the United States, responsible for one in six deaths worldwide. Although paclitaxel and docetaxel are still being heavily used in clinic for treatment of various cancers, the multi-drug resistance ...
Wang, Changwei
core +1 more source
Use of endophytic fungi in the Taxol anticancer drug production
Taxol is a drug used in the chemotherapy of breast, lung, ovarian, prostate, liver cancers, and in the treatment of rheumatoid arthritis. Taxol is obtained from Taxus spp. trees. It is found in low concentrations in the bark, needles and roots.
Hebert Jair Barrales-Cureño +1 more
doaj
Since numerous new taxoids active against multidrug resistant (MDR) tumors have been developed and their poor water-solubility is a very real problem in intravenous administration, we have designed and synthesized a series of novel water-soluble taxoid ...
Noguchi, Mayo +7 more
core +1 more source
Commonly used Paclitaxel (Taxol) in doses lower than 10 µM is not effective against CR4 cells and often increases their proliferation. In contrast, several new-generation taxoids induce dose-dependent inhibition of proliferation of these potent tumor ...
Roberto Bergamaschi (25663) +11 more
core +1 more source
1-Deoxypaclitaxel and abeo-Taxoids from the Seeds of Taxus mairei
A new paclitaxel derivative and two new 2(3→20)-abeo-taxoids were isolated from a methanol extract of the seeds of Taxus mairei, and their structures were established as 1-deoxypaclitaxel (1), 7β,10β-diacetoxy-2α,5α,13α-trihydroxy-2(3→20)-abeo-taxa-4(20),
Xiao-Tang Si (2649670) +5 more
core +1 more source
PECULIARITIES OF SECONDARY METABOLITES BIOSYNTHESIS IN PLANT CELL CULTURES
Plant cell culture is traditionally viewed as a unique artificially created biological system represented a heterogenous population of dedifferentiated cells.
A.M. NOSOV
doaj
Tasumatrols P-T, Five New Taxoids from Taxus Sumatrana
The phytochemical investigation of the more polar fractions from the leaves and twigs of Taxus sumatrana (Taxaceae) afforded five new taxane diterpene esters, tasumatrols P-T ( 1-5) possessing an 11(15 -> 1),11(10 - > 9)-diabeotaxane skeleton.
沈雅敬;簡慶德;郭曜豪;周昌弘 +1 more
core
Recent advances in <i>Taxus</i> molecular research: applications in genetic diversity, gene function and metabolic engineering. [PDF]
Jiang Y +7 more
europepmc +1 more source
Tri- and Bicyclic Taxoids from the Taiwanese Yew Taxus Sumatrana
Five new taxoids, including a new 2(3 -> 20)-abeo-taxane with a 6/10/6- membered ring system and four 3,8-seco-taxanes having a 6/12-membered ring system, were isolated from an acetone extract of the leaves and twigs of the Taiwanese yew (Taxus sumatrana,
LUH, LON-JE;LIAW, CHIA-CHING;CHEN, CHEN -TUNG;LIN, YUN-SHENG;CHIEN, CHING-TE;SHEN, YA-CHING +1 more
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