Results 91 to 100 of about 4,048 (209)
, 2014 Commonly used Paclitaxel (Taxol) in doses lower than 10 µM is not effective against CR4 cells and often increases their proliferation. In contrast, several new-generation taxoids induce dose-dependent inhibition of proliferation of these potent tumor ...
Roberto Bergamaschi (25663) +11 more
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HeliyonPaclitaxel is a potent anti-cancer drug that is mainly produced through semi-synthesis, which still requires plant materials as precursors. The content of paclitaxel and 10-deacetyl baccatin III (10-DAB) in Taxus yunnanensis has been found to differ from
Dong Wang +7 more
doaj +1 more source
Himalayan Yew – Exciting Conifer with Uncertain Future [PDF]
, 2018 39-40The Himalayan yew is a prime source of various taxoids including Taxol – a well known anti-cancer ...
Dar, Mohd. Aslam
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Design, Synthesis and Evaluation of Novel Taxane-Based Anticancer Agents [PDF]
, 2011 Taxol® (paclitaxel) and Taxotère® (docetaxel) are the most widely used pharmaceuticals in cancer chemotherapy. These drugs have been approved by the FDA for the treatment of advanced ovarian cancer, metastatic breast cancer, Kaposi Sarcoma, non-small ...
Li, Yuan
core
, 2002 Twenty seven different yew trees belonging to various genotypes and hybrids have been screened for their capacity to produce significant amounts of taxoids provided with biological activity in the tubulin test.
Meyer, M. +5 more
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1-Deoxypaclitaxel and abeo-Taxoids from the Seeds of Taxus mairei
, 2016 A new paclitaxel derivative and two new 2(3→20)-abeo-taxoids were isolated from a methanol extract of the seeds of Taxus mairei, and their structures were established as 1-deoxypaclitaxel (1), 7β,10β-diacetoxy-2α,5α,13α-trihydroxy-2(3→20)-abeo-taxa-4(20),
Xiao-Tang Si (2649670) +5 more
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Use of endophytic fungi in the Taxol anticancer drug production
Biotecnología Vegetal, 2014 Taxol is a drug used in the chemotherapy of breast, lung, ovarian, prostate, liver cancers, and in the treatment of rheumatoid arthritis. Taxol is obtained from Taxus spp. trees. It is found in low concentrations in the bark, needles and roots.
Hebert Jair Barrales-Cureño +1 more
doaj
Structural features of two taxoids from Taxus baccata L. growing in Turkey
, 2001 As a part of our ongoing research of the taxane-type constituents from T. baccata L. (Taxaceae) recorded in the Flora of Turkey, 2 alpha, 5 alpha, 10 beta -triacetoxy-14 beta-(2-methyl)-butryloxy-4(20),11-taxadiene (I) and taxusin (II) were isolated from
S. İde +5 more
core +1 more source
, 2016 Novel C2−C3‘N-linked macrocyclic taxoids 4 bearing an aromatic ring at position C2 were synthesized. These compounds, tethered between N3‘ and the C2-aromatic ring at the ortho, meta, or para position, were constructed by ring-closing metathesis.
Françoise Guéritte (2639503) +5 more
core +1 more source
, 2010 The production of taxuyunnanine C (Tc) (2 alpha, 5 alpha, 10 beta, 14 beta-tetraacetoxytaxa-4(20), 11(12)-diene) was significantly enhanced when Taxus chinensis cell cultures were treated with methyl jasmonate (MJA) or 2,3-dihydroxypropyl jasmonate ...
Xiao, Hong-Bin +3 more
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