Results 81 to 90 of about 4,048 (209)
, 2005 Since numerous new taxoids active against multidrug resistant (MDR) tumors have been developed and their poor water-solubility is a very real problem in intravenous administration, we have designed and synthesized a series of novel water-soluble taxoid ...
Noguchi, Mayo +7 more
core +1 more source
Production of taxoids in callus and cell suspensions of Taxus chinensis by using abiotic elicitors
Biotecnología Vegetal, 2004 Until now, several strategies have been developed to improve the production of secondary metabolites using plant cell cultures, manipulating the parameters of the environment, selecting high yielding cell clones and the use of elicitors.
Naivy Pérez +4 more
doaj
, 2003 Four taxoids (taxusin, baccatin VI,baccatin III and 1beta-hydroxybaccatin I) and five lignans (lariciresinol, taxiresinol, 3'-demethylisolariciresinol-9'-hydroxyisopropyl ether, isolariciresinol and 3-demethylisolariciresinol) were isolated from the ...
Yesilada, E +3 more
core +1 more source
PECULIARITIES OF SECONDARY METABOLITES BIOSYNTHESIS IN PLANT CELL CULTURES
International Journal of Secondary Metabolite, 2014 metabolites formation in plant cell cultures of Panax spp., (ginsenosides); Dioscorea deltoidea (steroid glycosides); Ajuga reptans, Serratula coronata, Rhaponticum carthamoides (ecdisteroids); Polyscias spp., (triterpene glycosides), Taxus spp. (taxoids)
A.M. NOSOV
doaj +2 more sources
A Meta-analysis of Platinum Plus Taxanes Regimen on Treating Advanced Non-small Cell Lung Cancer
Chinese Journal of Lung Cancer, 2009 Background and objective The platinum-based plus a third-generation agent doublet chemotherapy regimen has been recommended as the standard first-line chemotherapy for advanced NSCLC by ASCO and NCCN.
Ning ZHU +3 more
doaj
, 2003 A series of 2-methyl taxoids were synthesized and essayed for growth inhibition experiments conducted in human ovarian cancer cell line A2780wt and its counterparts A2780cis, A2780tax, and A2780adr, resistant to cisplatin, paclitaxel, and doxorubicin ...
Bernacki RJ +8 more
core
, 2004 The success of paclitaxel and docetaxel as anticancer agents stimulated the search of innovative analogs endowed with more favorable pharmacol. profile.
M.L. Gelmi +7 more
core +1 more source
Taxuspinanane G from the Aerial Parts of Taxus baccata L. Growing in Iran
Journal of Medicinal Plants, 2008 Background: The discovery of paclitaxel (Taxol®) as a potent anticancer drug from Taxus brevifolia has encouraged several groups all over the world to conduct research work on other Taxus species, in order to isolate potentially more effective paclitaxel
MR Verdian - Rizi +4 more
doaj
, 2017 According to the National Cancer Institute, the number of people living with cancer is expected to rise to 19 million by 2024. While significant advancements have been made in chemotherapy, combating drug resistance and cancer stem cells have remained a ...
Wang, Xin
core
Production of Biologically Active Taxoids by a Callus Culture of Taxus cuspidata
, 2016 Ten known taxoids, paclitaxel, 7-epi-taxol, taxol C, baccatin VI, taxayuntin C, taxuyunnanine C and its analogues (2−5), and yunnanxane (6), and an abietane, taxamairin A, were produced in the callus culture of Taxus cuspidata cultivated on a modified ...
Katutoshi Hirose (2685235) +11 more
core +1 more source