Taxuspinanane G from the Aerial Parts of Taxus baccata L. Growing in Iran
Background: The discovery of paclitaxel (Taxol®) as a potent anticancer drug from Taxus brevifolia has encouraged several groups all over the world to conduct research work on other Taxus species, in order to isolate potentially more effective paclitaxel
MR Verdian - Rizi +4 more
doaj
Use of endophytic fungi in the Taxol anticancer drug production
Taxol is a drug used in the chemotherapy of breast, lung, ovarian, prostate, liver cancers, and in the treatment of rheumatoid arthritis. Taxol is obtained from Taxus spp. trees. It is found in low concentrations in the bark, needles and roots.
Hebert Jair Barrales-Cureño +1 more
doaj
PECULIARITIES OF SECONDARY METABOLITES BIOSYNTHESIS IN PLANT CELL CULTURES
Plant cell culture is traditionally viewed as a unique artificially created biological system represented a heterogenous population of dedifferentiated cells.
A.M. NOSOV
doaj
Recent advances in the strategic incorporation of fluorine into new-generation taxoid anticancer agents. [PDF]
Jayanetti K +4 more
europepmc +1 more source
Directly comparing randomized and real-world controls in adjuvant breast cancer. [PDF]
Walker B +6 more
europepmc +1 more source
4 Metabolism and pharmacology of taxoids
Publisher Summary This chapter presents metabolism and pharmacology of taxoids. Three main modifications occur in taxoids when they are introduced in the organism—namely, (1) epimerization, (2) hydrolysis, and (3) hydroxylation. After 72 h of incubation, the ratio of 7-epi-paclitaxel to paclitaxel varies from 0.36 to 0.48 in the cell and from 0.25 to
openaire +1 more source
Enhanced Antiproliferative Activity of Docetaxel by Extremely Low Frequency Electromagnetic Fields in MCF-7 Breast Cancer Cells. [PDF]
Vesal M +5 more
europepmc +1 more source
Risk Factors and Clinical Significance of Grade ≥3 Neutropenia During the First Cycle of Cabazitaxel Therapy With Primary Pegfilgrastim Prophylaxis in Metastatic Castration-resistant Prostate Cancer. [PDF]
Sato R +4 more
europepmc +1 more source
Enhancement of paclitaxel production by Neopestalotiopsis vitis via optimization of growth conditions. [PDF]
Rezazadeh H +4 more
europepmc +1 more source
Cost-Effectiveness Analysis of <sup>177</sup>Lu-PSMA-617 Versus Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer from a U.S. Health Care Perspective. [PDF]
Gogebakan KC +5 more
europepmc +1 more source

