Results 61 to 70 of about 3,991 (207)
Oncology in Clinical PracticeINTRODUCTION: Glucose metabolism disorders are associated with an increased risk of breast cancer (BC), which is the most common cancer in women. The association between metabolic disorders and BC is well established.
Joanna Kujawska +4 more
doaj +1 more source
Canadian Respiratory Journal, Volume 2025, Issue 1, 2025.Introduction Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disease with a poor prognosis and no effective pharmacological treatments. Cytokines are a class of small‐molecule proteins with diverse biological activities. Many cytokines—most notably transforming growth factor β—have been demonstrated to play an important role ...
Chenyou Shen +11 more
wiley +1 more source
, 2016 Two new taxoids, 13,15-epoxy-13-epi-taxayunnasin A (1) and taxchinin N (2), were isolated from the leaves and stems of Taxus chinensis. Compound 2 is the first taxoid to be reported with an α,β-unsaturated lactone at C-4, C-5, C-20, and C-2.
Yu Zhao (104852) +9 more
core +1 more source
Chemistry – A European Journal, Volume 30, Issue 49, September 2, 2024.We report on new and conjugatable tripodal compounds which open up the possibility for multiplexing with BODIPY tags for studies by confocal microscopy and 2P FLIM with structural and photochemical predictions underpinned by TD‐DFT calculations. Abstract A range of novel BODIPY derivatives with a tripodal aromatic core was synthesized and characterized
Marina Lledos +9 more
wiley +1 more source
ChemCatChem, Volume 16, Issue 9, May 8, 2024.A Taxus 2‐O‐benzoyltransferase (mTBT), assisted by CoA, is used to biocatalytically deconstruct older‐generation paclitaxel precursors by removing the 2‐O‐benzoyl group from baccatin III or one of its 10‐O‐acyl analogs. mTBT then appends various non‐natural (m‐substituted)benzoyl groups, transferring them from CoA thioesters to the debenzoylated ...
Aimen Al‐Hilfi +4 more
wiley +1 more source
Three Decades of Taxanes: Exploring the Next Frontier
Scientia PharmaceuticaTaxanes, such as paclitaxel and docetaxel, are microtubule-stabilizing agents widely used in oncology, either as monotherapy or in combination regimens.
Rita I. L. Catarino +4 more
doaj +1 more source
, 2008 The taxuyunnanine C (Tc) was greatly enhanced when Taxus chinensis cell cultures were elicited by methyl jasmonate or 2,3-dihydroxypropyl jasmonate (DHPJA), a newly synthesized jasmonate analog in combination with in situ absorption.
张卫, 肖红斌, 岳向国, 高明波
core
Postirradiation Multiple Minute Digitate Porokeratosis: Case Report
Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018 Docetaxel is a second-generation taxane commonly used in the treatment of advanced malignant tumours such as breast adenocarcinoma. We describe the case of a 67-year-old female undergoing adjuvant chemotherapy with docetaxel for invasive ductal carcinoma
Joana Lima, Marta Sousa, Pedro Andrade
doaj +1 more source
, 2016 A series of novel macrocyclic taxoids 6 and 6‘ bearing 16-, 17-, and 18-membered rings connecting the substituents at the C-2 and C-3‘ positions were designed and synthesized. The syntheses of these macrocycles 6 and 6‘ were accomplished using the highly
Songnian Lin (2435152) +6 more
core +1 more source
Acta Cirúrgica Brasileira, 2009 PURPOSE: Many patients with metastatic bone disease have to use radiopharmaceuticals associated with chemotherapy to relieve bone pain. The aim of this study was to assess the influence of docetaxel on the biodistribution of samarium-153-EDTMP in bones ...
Arthur Villarim Neto +6 more
doaj +1 more source