Results 71 to 80 of about 4,048 (209)

Taxoids and Abietanes from Callus Cultures of Taxus cuspidata

, 2016
Seventeen known taxoids and 10 abietanes were isolated from the dark brown callus culture of Taxus cuspidata cultivated on a modified Gamborg's B5 medium with 0.5 or 1.0 mg/L NAA.
Katutoshi Hirose (2685235), Mutumi Kitabatake (2685244), Hajime Fujisawa (2685247), Nobuhide Ito (2685250), Junichi Sakai (77403), Liming Bai (2685241), Masayoshi Ando (2685238), Jungui Dai (610572), Akihiro Tomida (133017), Jiao Bai (737971), Shujun Zhang (314599), Takashi Tsuruo (2367658)   +11 more
core   +1 more source

New Efficient Construction of the ABC Core of the Taxoids via a Sequence of Consecutive Cobalt(I)-Mediated [2 + 2 + 2] and [4 + 2] Cyclizations

, 2016
A new and efficient sequence of two consecutive cyclizations, a cobalt(I)-mediated [2 + 2 + 2] cyclotrimerization and a Diels−Alder reaction, is proposed to allow the formation of the ABC core of the taxoids in 65% overall yield, starting from an acyclic
Marc Petit (1470346), Corinne Aubert (511920), Max Malacria (1737190), Gaëlle Chouraqui (2718955), Phannarath Phansavath (1652164)   +4 more
core   +1 more source

Postirradiation Multiple Minute Digitate Porokeratosis: Case Report

Revista da Sociedade Portuguesa de Dermatologia e Venereologia, 2018
Docetaxel is a second-generation taxane commonly used in the treatment of advanced malignant tumours such as breast adenocarcinoma. We describe the case of a 67-year-old female undergoing adjuvant chemotherapy with docetaxel for invasive ductal carcinoma
Joana Lima, Marta Sousa, Pedro Andrade
doaj   +1 more source

1998 Alfred Bader Award Lecture Tangents and targets: The synthetic highway from natural products to medicine

, 1999
Synthetic studies directed toward various classes of compounds including taxoids and enediyne systems are described. These investigations include tether-controlled imtramolecular Diels-Alder reactions, carbometallation routes to dienes and furans, the ...
Alex G Fallis
core   +1 more source

Biodistribution of samarium-153-EDTMP in rats treated with docetaxel Biodistribuição de EDTMP-153-samário em ratos tratados com docetaxel

Acta Cirúrgica Brasileira, 2009
PURPOSE: Many patients with metastatic bone disease have to use radiopharmaceuticals associated with chemotherapy to relieve bone pain. The aim of this study was to assess the influence of docetaxel on the biodistribution of samarium-153-EDTMP in bones ...
Arthur Villarim Neto, Maria Kadja Meneses Torres Açucena, Kércia Regina Santos Gomes Pereira, Amália Cínthia Meneses Rêgo, Ítalo Medeiros Azevedo, Mário Bernardo-Filho, Aldo Cunha Medeiros   +6 more
doaj   +1 more source

Cost-effectiveness analysis of the introduction of S-1 therapy for first-line metastatic breast cancer treatment in Japan: results from the randomized phase III SELECT BC trial

BMC Cancer, 2017
Background This study evaluated the cost-effectiveness of replacing standard intravenous therapy (taxane) with oral S-1 therapy for first-line metastatic breast cancer treatment.
Takeru Shiroiwa, Takashi Fukuda, Kojiro Shimozuma, Mitsuko Mouri, Yasuhiro Hagiwara, Takuya Kawahara, Shozo Ohsumi, Yasuo Hozumi, Yoshiaki Sagara, Yasuo Ohashi, Hirofumi Mukai   +10 more
doaj   +1 more source

Survival-related profile, pathways, and transcription factors in ovarian cancer.

PLoS Medicine, 2009
BackgroundOvarian cancer has a poor prognosis due to advanced stage at presentation and either intrinsic or acquired resistance to classic cytotoxic drugs such as platinum and taxoids.
Anne P G Crijns, Rudolf S N Fehrmann, Steven de Jong, Frans Gerbens, Gert Jan Meersma, Harry G Klip, Harry Hollema, Robert M W Hofstra, Gerard J te Meerman, Elisabeth G E de Vries, Ate G J van der Zee   +10 more
doaj   +1 more source

Macrocycle Formation by Ring-Closing Metathesis. Application to the Syntheses of Novel Macrocyclic Taxoids

, 2016
A series of novel macrocyclic taxoids 6 and 6‘ bearing 16-, 17-, and 18-membered rings connecting the substituents at the C-2 and C-3‘ positions were designed and synthesized. The syntheses of these macrocycles 6 and 6‘ were accomplished using the highly
Songnian Lin (2435152), Xudong Geng (2402215), Christopher P. Borella (2435167), Michael L. Miller (2435158), John J. Walsh (1512973), Iwao Ojima (295240), Tadashi Inoue (1631458)   +6 more
core   +1 more source

Efeitos colaterais cutâneos de quimioterapia com taxanos: O ponto de vista do dermatologista Cutaneous adverse reactions to chemotherapy with taxanes: The dermatologist's point of view

Anais Brasileiros de Dermatologia, 2011
Taxanos são drogas quimioterápicas cada vez mais utilizadas no tratamento adjuvante de um grande número de cânceres, principalmente câncer de mama e de pulmão.
Aline Donati, Luiz Guilherme Martins Castro   +1 more
doaj   +1 more source

Natural Based Anticancer Drugs and Their Worthiness

Hospital Practices and Research, 2017
With the prevalence of every type of cancer increasing globally, the inability to treat and the severe side effects caused by chemotherapy and radiotherapy are some of the biggest problems facing cancer patients and their physicians.1 Many herbal ...
Kamran Hajinabi
doaj   +1 more source