Results 41 to 50 of about 3,991 (207)
Docetaxel-induced Scleroderma in A Breast Cancer Patient: A Case Report
European Journal of Breast Health, 2015 Paclitaxel and docetaxel are antineoplastic drugs derived from the yew tree, Taxus brevifolia. They are the members of the taxane family and act by inhibiting mitotic activity due to the suppression of microtubule depolymerization.
Murat Özgür Kılıç +3 more
doaj +1 more source
An Unusual Case Presentation on Docetaxel Induced Lung Injury
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT Docetaxel can rarely cause acute interstitial lung injury early in therapy. New‐onset cough, fever, or dyspnea after chemotherapy should prompt immediate evaluation, exclusion of infection, and high‐resolution CT imaging. Early drug withdrawal and timely corticosteroid therapy can result in rapid clinical recovery and prevent serious morbidity.
Soorej Balan Kaliyath +7 more
wiley +1 more source
Design, Synthesis, and Biological Evaluation of Novel C14−C3′BzN-Linked Macrocyclic Taxoids
, 2016 Novel macrocyclic paclitaxel congeners were designed to mimic the bioactive conformation of paclitaxel. Computational analysis of the “REDOR-Taxol” structure revealed that this structure could be rigidified by connecting the C14 position of the baccatin ...
Ralph J. Bernacki (2402203) +12 more
core +2 more sources
Phytochemicals in Food and Medicine, Volume 1, Issue 1, March 2026.The orthoquinone metabolites from plants have antimicrobial, antioxidant, antiviral, cytotoxic, and anti‐inflammatory effects. ABSTRACT The structural diversity of natural products is vast and fascinating, and they have been recognized as an enormously diverse source of new lead compounds.
Hidayat Hussain +5 more
wiley +1 more source
, 2008 Aim: To develop an artificial neural network model for predicting the resistance index (RI) of taxoids. Methods: A dataset of 63 experimental data points were compiled from published studies and randomly subdivided into training and external test sets ...
Guang-bo GE +14 more
core +1 more source
BMC Plant Biology, 2019 Background Taxol is an efficient anticancer drug; however, the accumulation of taxoids can vary hugely among Taxus species. The mechanism underlying differential accumulation of taxoids is largely unknown. Thus, comparative analysis of the transcriptomes
Ting Zhou +7 more
doaj +1 more source
Biological Activity and Chemistry of Taxoids from the Japanese Yew, Taxus cuspidata⊥
, 2016 Approximately 120 taxoids have been isolated to date from the Japanese yew, Taxus cuspidata. These taxoids possess various skeletons containing 5/7/6-, 6/10/6-, 6/5/5/6-, 6/8/6-, or 6/12-membered ring systems.
Jun'ichi Kobayashi (2454499) +1 more
core +1 more source
Synthesis of Taxane ABC Tricyclic Skeleton from Lycoctonine
Natural Product Communications, 2012 A new conversional synthesis of the ABC ring system of taxoids from the C 19 -diterpenoid alkaloid lycoctonine was developed in 6 steps with 2% overall yield. The distinctive features of the conversion include pinacol rearrangement, enlargement of ring B,
Xiao-Xia Liang +3 more
doaj +1 more source
Breast, 2020 Purpose: Discrepancies between clinicians’ assessment of chemotherapy-induced peripheral neuropathy (CIPN) and patient-reported outcomes (PRO) have been described, though the underlying reasons are unknown. Our objective was to identify potential patient-
Teresa M. Salgado +13 more
doaj +1 more source