Results 101 to 110 of about 58,325 (234)

Phytochemical Nanoparticles for the Treatment of Neurological Disorders

open access: yesPhytochemical Analysis, Volume 36, Issue 7, Page 1918-1935, October 2025.
ABSTRACT Neurological disorders impose a significant burden on the healthcare systems. The latest published data by WHO indicated that stroke was the second leading cause of death globally in 2020, with Alzheimer's disease (AD) and other dementias in the seventh position.
Touraj Ehtezazi, Satyajit D. Sarker
wiley   +1 more source

Traditional Chinese medicine herbal mixture LQ arrests FUCCI-expressing HeLa cells in G₀/G₁ phase in 2D plastic, 2.5D Matrigel, and 3D Gelfoam culture visualized with FUCCI imaging. [PDF]

open access: yes, 2015
We used the fluorescence ubiquitination-based cell cycle indicator (FUCCI) to monitor cell cycle arrest after treatment of FUCCI-expressing HeLa cells (FUCCI-HeLa) with a traditional Chinese medicine (TCM) herbal mixture LQ, previously shown to have anti-
Bouvet, Michael   +4 more
core   +2 more sources

Herbal Medicine for Colorectal Cancer Treatment: Molecular Mechanisms and Clinical Applications

open access: yesCell Proliferation, Volume 58, Issue 10, October 2025.
Colorectal cancer is a prevalent gastrointestinal tumour and the second deadliest cancer worldwide, affecting approximately 10% of all cancers and cancer‐related deaths. Current clinical methods for treating CRC cause gastrointestinal abnormalities and myelosuppression.
Zuqing Su   +5 more
wiley   +1 more source

Profiles and Bioinformatics Analysis of Differentially Expressed Circrnas in Taxol-Resistant Non-Small Cell Lung Cancer Cells

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Circular RNAs (circRNAs) act as microRNA (miRNA) sponges that regulate gene expression and are involved in physiological and pathological processes.
Ning Xu   +7 more
doaj   +1 more source

Restoration of Taxol Sensitivity of Multidrug-Resistant Cells by the Cyclosporine SDZ PSC 833 and the Cyclopeptolide SDZ 280-446 [PDF]

open access: yes, 2017
Background: Taxol, a promising agent for the treatment of cancer, has entered phase II clinical trials. Nevertheless, it belongs to the class of compounds that show impaired retention in multidrug-resistant cells expressing P-glycoprotein (Pgp), a drug ...
Jachez, Bénédicte   +2 more
core  

Genomic Signatures of Climate‐Driven (Mal)Adaptation in an Iconic Conifer, the English Yew (Taxus baccata L.)

open access: yesEvolutionary Applications, Volume 18, Issue 10, October 2025.
ABSTRACT The risk of climate maladaptation is increasing for numerous species, including trees. Developing robust methods to assess population maladaptation remains a critical challenge. Genomic offset approaches aim to predict climate maladaptation by characterizing the genomic changes required for populations to maintain their fitness under changing ...
Thomas Francisco   +16 more
wiley   +1 more source

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

open access: yesPlant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang   +8 more
wiley   +1 more source

Salicylic acid as an effective elicitor for improved taxol production in endophytic fungus Pestalotiopsis microspora.

open access: yesPLoS ONE, 2019
Salicylic acid (SA) is an effective elicitor to increase taxol production in Pestalotiopsis microspora. Addition of SA at the concentration of 300 μM yielded taxol 625.47 μg L-1, 45- fold higher than that of the control.
Kamalraj Subban   +4 more
doaj   +1 more source

Comparative metabolomics reveals the metabolic variations between two endangered Taxus species (T. fuana and T. yunnanensis) in the Himalayas

open access: yesBMC Plant Biology, 2018
Background Plants of the genus Taxus have attracted much attention owing to the natural product taxol, a successful anti-cancer drug. T. fuana and T. yunnanensis are two endangered Taxus species mainly distributed in the Himalayas.
Chunna Yu   +7 more
doaj   +1 more source

The prognostic role of VEGF in head and neck squamous cell carcinoma [PDF]

open access: yes, 2017
Emerging from potentially malignant disorders that in most cases will never become cancerous, head and neck squamous cell carcinoma (HNSCC) is a cancer that is extremely difficult to diagnose early.
Mathew, Rohit Thomas
core  

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