Results 81 to 90 of about 327,793 (259)

A Friendly Relationship between Endophytic Fungi and Medicinal Plants: A Systematic Review [PDF]

, 2016
Endophytic fungi or endophytes exist widely inside the healthy tissues of living plants, and are important components of plant micro-ecosystems. Over the long period of evolution, some co-existing endophytes and their host plants have established a ...
Abd_Allah, Ahmad, Amna, Bacon, Barazani, Bashyal, Behie, Bittleston, Bussaban, Camatti-Sartori, Cao, Cao, Carroll, Cavaglieri, Chakravarthi, Chen, Chen, Chen, Chen, Chen, Chen, Chen, Chithra, Chutima, Cui, D'Amico, Dai, Deng, Dingle, Duan, Eyberger, Faeth, Fan, Firáková, Gangadevi, Gangadevi, Gange, Gao, Gunatilaka, Guo, Guo, Guo, Gómez-Vidal, Harper, Hartley, Herrera-Carrillo, Huang, Huang, Jiang, Ju, Khan, Kim, Kour, Kozyrovska, Kumaran, Kumaran, Kusari, Kusari, Kusari, Kusari, Kusari, Kusari, Li, Li, Li, Li, Li, Li, Liu, Liu, Lu, Maciá-Vicente, Maehara, Meng, Ming, Mo, Moricca, Nascimento, Nejad, Osono, Pan, Puri, Puri, Qiu, Qiu, Redman, Rehman, Ren, Richardson, Rodrigues, Rodriguez, Rodriguez, Saikkonen, Saikkonen, Senthil Kumaran, Sherameti, Shrestha, Shwab, Shweta, Sieber, Silva, Song, Stierle, Stierle, Strobel, Strobel, Strobel, Sumarah, Sun, Sun, Suryanarayanan, Tan, Tang, Tofern, Torres, Unterseher, Venkatachalam, Wang, Wang, Wang, Wang, Wang, Wang, Waqas, Weyens, Wu, Yan, Yang, Yang, Yin, Yu, Zeng, Zhang, Zhang, Zhang, Zhang, Zhang, Zhang, Zhao, Zhao, Zhou, Zhou   +141 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, Volume 19, Issue 12, Page 3665-3684, December 2025.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Identification of Taxol-producing endophytic fungi isolated from Salacia oblonga through genomic mining approach

Journal of Genetic Engineering and Biotechnology, 2015
The most promising anti-tumor agent developed in the past three decades is Taxol. It is proven to be effective against many cancers. It is necessary to isolate pharmacologically potent endophytic microbial strains from medicinal plants with special ...
G. Roopa, M.C. Madhusudhan, K.C.R. Sunil, N. Lisa, R. Calvin, R. Poornima, N. Zeinab, K.R. Kini, H.S. Prakash, N. Geetha   +9 more
doaj   +1 more source

Chemoenzymatic Synthesis of Cryptophycin Anticancer Agents by an Ester Bond-Forming Non-ribosomal Peptide Synthetase Module [PDF]

, 2011
Cryptophycins (Crp) are a group of cyanobacterial depsipeptides with activity against drug-resistant tumors. Although they have been shown to be promising, further efforts are required to return these highly potent compounds to the clinic through a new ...
Bolduc, Kyle L., Ding, Yousong, Håkansson, Kristina, Rath, Christopher M., Sherman, David H.   +4 more
core   +1 more source

The role of octadecanoids and functional mimics in soybean defense responses [PDF]

, 2003
Oxylipins of the jasmonate pathway and synthetic functional analogs have been analyzed for their elicitor like activities in an assay based on the induced accumulation of glyceollins, the phytoalexins of soybean (Glycine max L.), in cell suspension ...
Czarnecka E., Ellard-Ivey M., Graham T.L., Latunde-Dada A.O., Nojiri H., Schröder J., Schüler G., Siedow J.N.   +7 more
core   +1 more source

Optimizing the biosynthesis of oxygenated and acetylated Taxol precursors in Saccharomyces cerevisiae using advanced bioprocessing strategies

Biotechnology and Bioengineering, 2020
Taxadien‐5α‐hydroxylase and taxadien‐5α‐ol O‐acetyltransferase catalyze the oxidation of taxadiene to taxadien‐5α‐ol and subsequent acetylation to taxadien‐5α‐yl‐acetate in the biosynthesis of the blockbuster anticancer drug, paclitaxel (Taxol®). Despite
Laura E. Walls, K. Malcı, Behnaz Nowrouzi, Rachel A. Li, Leo d’Espaux, J. Wong, Jonathan A Dennis, A. J. Semiao, Stephen Wallace, J. Martínez, J. Keasling, L. Rios‐Solis   +11 more
semanticscholar   +1 more source

Identification of a Pair of Linear or Cyclic Naturally Inspired Bifunctional Lipopeptide Antibiotics That Overcome Antimicrobial Resistance

Advanced Science, Volume 12, Issue 45, December 4, 2025.
The underexplored bacterial genus Aquimarina harbors a large biosynthetic potential for discovering new antibiotics. Here, the authors identify a pair of linear or cyclic bifunctional cationic lipopeptide antibiotics, aquicidine L and C4, inspired by the aquicidine gene cluster from Aquimarina.
Lei Li, Yiwen Zhou, Yuzhu Wu
wiley   +1 more source

Cloning and expression of a human kinesin heavy chain gene: interaction of the COOH-terminal domain with cytoplasmic microtubules in transfected CV-1 cells. [PDF]

, 1992
To understand the interactions between the microtubule-based motor protein kinesin and intracellular components, we have expressed the kinesin heavy chain and its different domains in CV-1 monkey kidney epithelial cells and examined their distributions ...
Bernstein, HD, Hom-Booher, N, McCaffrey, G, Navone, F, Niclas, J, Sparks, L, Vale, RD   +6 more
core  

A re-assessment of Taxomyces andreanae, the alleged taxol-producing fungus, using comparative genomics

IMA Fungus, 2022
The monotypic “bulbilliferous hyphomycete” genus Taxomyces was erected in 1993 for a fungal endophyte isolated from the Yew tree Taxus brevifolia and named Taxomyces andreanae. This fungus was reported to produce the plant-derived anti-cancer drug taxol.
Tian Cheng, Miroslav Kolařík, Luis Quijada, Marc Stadler   +3 more
doaj   +1 more source

The Genome of Phoebe zhennan (Lauraceae) and Comparative Genomics of Phoebe 楠木(樟科)基因组与楠属植物比较基因组学研究

Integrative Conservation, Volume 4, Issue 4, Page 584-599, December 2025.
Phoebe zhennan is a Chinese endemic and valuable timber species of Phoebe (Lauraceae). We present a chromosome‐level genome assembly of P. zhennan. Our research provides novel insights into the genome evolution of Phoebe, including whole‐genome duplication, phylogenetic relationships of magnoliids, and key MYB regulatory genes involved in lignin ...
Mao Yameng, Zou Dianyang, Li Lang, Li Jie   +3 more
wiley   +1 more source