Results 121 to 130 of about 13,784 (200)

IP3R1 dysregulation via mir-200c-3p/SSFA2 axis contributes to taxol resistance in head and neck cancer [PDF]

open access: yes
Head and neck cancer (HNC) is the sixth most common malignancy worldwide. Although current modalities offer a wide variety of therapy choices, head and neck carcinoma has poor prognosis due to its diagnosis at later stages and development of resistance ...
Gundogdu, Betül   +3 more
core   +1 more source

Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation

open access: yesInternational Journal of Nanomedicine, 2013
Liangcen Chen, Xianyi Sha, Xinyi Jiang, Yanzuo Chen, Qiuyue Ren, Xiaoling FangDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, ChinaAbstract: The aim of this work was to establish a novel polymeric mixed micelle composed of ...
Fang X   +5 more
doaj  

Polo like kinase 2 tumour suppressor and cancer biomarker: new perspectives on drug sensitivity/resistance in ovarian cancer [PDF]

open access: yes, 2012
The polo-like kinase PLK2 has recently been identified as a potential theranostic marker in the management of chemotherapy sensitive cancers. The methylation status of the PLK2 CpG island varies with sensitivity to paclitaxel and platinum in ovarian ...
Mcneish, I.   +13 more
core  

A novel paclitaxel-loaded poly(D,L-lactide-co-glycolide)-Tween 80 copolymer nanoparticle overcoming multidrug resistance for lung cancer treatment

open access: yesInternational Journal of Nanomedicine, 2016
Xun Yuan,1,* Wenxiang Ji,2,* Si Chen,1 Yuling Bao,3 Songwei Tan,3 Shun Lu,2 Kongming Wu,1 Qian Chu11Department of Oncology, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 2Lung Tumor Clinical Medical ...
Yuan X   +7 more
doaj  

Syntheses and Bioactivities of Targeted and Conformationally Restrained Taxol Analogs [PDF]

open access: yes, 2004
Taxol (1) was first isolated from the bark of the Pacific yew about 35 years ago by Drs. Wall and Wani. Although its development as an anticancer agent was delayed by numerous reasons, including its scarcity and insolubility, the discovery of its tubulin-
Liu, Changhui
core  

Analysis of Differential Gel Electrophoresis of Paclitaxol Resistant and Sensitive Lung Adenocarcinoma Cells' Secretome

open access: yesChinese Journal of Lung Cancer, 2009
Background and objective Paclitaxol (PTX) resistance is one of main factors which affect the outcome of chemotherapy of lung adenocarcinoma. The aim of this study is to compare the secreted protein expression profiles between Paclitaxol (PTX) resistant ...
Tianqing CHU   +5 more
doaj  

Caracterización del perfil quimiosensibilidad y del estado de ampliación génica de un panel de líneas celulares de origen tumoral pulmonar

open access: yesRevista Colombiana de Biotecnología, 2013
Título en Ingles: Characterization of chemosensitivity profile and gene amplification status of a panel of lung cancer cell lines Título Corto: Amplificación génica y quimiosensibilidad en líneas celulares de cáncer de pulmón Resumen: En este trabajo se ...
Sandra Johanna Morantes   +3 more
doaj  

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