Results 101 to 110 of about 2,363,919 (190)

Cocrystal@protein-anchoring nanococktail for combinatorially treating multidrug-resistant cancer

Acta Pharmaceutica Sinica B
Multidrug resistance (MDR), the major mechanism by which various cancers develop specific resistance to therapeutic agents, has set up enormous obstacles to many forms of tumor chemotherapy.
Jiahui Zou, Xuyang Xing, Chao Teng, Qingling Zhao, Wei He, Xuri Wu, Yuanzheng Xia   +6 more
doaj   +1 more source

Blocking lncRNA HCG18 re-sensitizes Taxol resistant lung cancer cells to Taxol through modulating the miR-34a-5p/HDAC1 axis

Lung cancer is one of the most frequently diagnosed cancers worldwide, associated with a poor survival rate. Taxol (Paclitaxel) is commonly used as a chemotherapeutic treatment for advanced lung cancers.
Juan Wang (115708), Qiuyue Xu (8931536), Lin Liu (74495), Kai Yang (73590), Zijie Liu (2319538), Xiaoyu Luo (575148), Rong Gong (3496781), Haoyu Li (1672648), Fujun Zhang (588079), Yunmin Xu (18507480)   +9 more
core   +1 more source

Septins, polyglutamylated tubulin and resistance to Taxol

, 2015
L’émergence de phénomènes de résistance au paclitaxel (Taxol®), un agent stabilisateur de microtubules (MTs), est un obstacle majeur au succès de cette molécule dans les chimiothérapies anticancéreuses et limite son utilisation.
Targa, Benjamin
core  

Expressions of miRNA27a and miRNA451 in ovarian cancer and breast cancer cells and its correlation with drug resistance by targeting MDR1/P-glycoprotein

Zhongguo aizheng zazhi, 2015
Background and purpose: Resistance of cancer cells to chemotherapy is a major clinical obstacle to successful treatment and leads to poor prognosis for the patients.
李智敏, 罗喜平, 曾俐琴
doaj  

XIST lost induces ovarian cancer stem cells to acquire taxol resistance via a KMT2C-dependent way. [PDF]

Cancer Cell Int, 2020
Huang R, Zhu L, Zhang Y.
europepmc   +1 more source

Taxol Reduces Cytosolic E-Cadherin and Beta-Catenin Levels in Nasopharyngeal Carcinoma Cell Line Tw-039: Cross-Talk between the Microtubule- and Actin-Based Cytoskeletons

, 2008
Taxol affects microtubule dynamics by promoting microtubule assembly. To obtain a better insight into possible cross- talk between the microtubule- and actin-based cytoskeletons, we studied the short-term effects of Taxol treatment on the expression of ...
LOU, PEI-JEN;CHEN, WEN-PIN;LIN, CHIN- TARNG;CHEN, HUI-CHIN;WU, JIAHN-CHUN, 婁培人;陳文彬;林欽塘;陳慧瑾;吳建春   +1 more
core  

LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a. [PDF]

Biosci Rep, 2020
Duan Y, Chen J, Yang Y, Qu Z, Lu Y, Sun D.   +5 more
europepmc   +1 more source

Correction: LncRNA HOTAIR contributes Taxol-resistance of hepatocellular carcinoma cells via activating AKT phosphorylation by down-regulating miR-34a. [PDF]

Biosci Rep, 2021
europepmc   +1 more source

Characterization of a taxol-resistant hepatocellular carcinoma cell line (QGY-TR 50)

, 2001
Cancer chemotherapy with taxol often fails due to acquired resistance of cancer cells, which is frequently associated with an overexpression of P-glycoprotein and alterations of ß-tubulin.
Zhou, Jing
core  

Pluronic P105/F127 mixed micelles for the delivery of docetaxel against Taxol-resistant non-small cell lung cancer: optimization and in vitro, in vivo evaluation

International Journal of Nanomedicine, 2013
Liangcen Chen, Xianyi Sha, Xinyi Jiang, Yanzuo Chen, Qiuyue Ren, Xiaoling FangDepartment of Pharmaceutics, School of Pharmacy, Fudan University, Shanghai, ChinaAbstract: The aim of this work was to establish a novel polymeric mixed micelle composed of ...
Fang X, Ren Q, Chen Y, Jiang X, Sha X, Chen L   +5 more
doaj