Results 141 to 150 of about 22,844 (235)

Hippo Signaling in the Lung: A Tale of Two Effectors-Yap Drives Airway Fate and Taz Drives Alveolar Differentiation. [PDF]

Cells
Warren R, De Langhe SPJ.
europepmc   +1 more source

Mitophagy and Ubiquitination Coordinate Context‐Specific Mitochondrial Quality Control and EMT/MET Plasticity to Drive Cancer Cell Invasion

Advanced Science, Volume 13, Issue 16, 18 March 2026.
Metastatic invasion emerges when tumor‐intrinsic programs and microenvironmental forces converge on mitochondrial quality control. A context‐stratified framework links mtROS, mtDNA integrity, mechanics and nutrient/oxygen cues to fission–fusion remodeling, mtUPR and mitophagy.
Bin‐Hsu Mao, Bo‐Kai Su, Ying‐Jan Wang, Ting‐Yuan Tu   +3 more
wiley   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, Volume 13, Issue 14, 9 March 2026.
CGRP interacts with HMEC‐1 by binding to surface receptors, influencing the downstream FAK/AKT/VEGF signaling pathway, and promoting the secretion of ANGPTL4 from vascular endothelial cells into the bone microenvironment. This, in turn, regulates the differentiation of BMSCs into osteoblasts, thus promoting bone formation. ABSTRACT Bone angiogenesis is
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

The Stiff Side of Cancer: How Matrix Mechanics Rewrites Non-Coding RNA Expression Programs. [PDF]

Noncoding RNA
Campos-Parra AD, Puente-Rivera J, López-Camarillo C, Nuñez-Olvera SI, Hernández Nava N, Macias GA, Silva-Cázares MB.   +6 more
europepmc   +1 more source

Bioprinted Excitable Tissues with Multistimulation Systems for Promoting Function and Maturation

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
This review provides an overview of stimulation strategies used to enhance the functional maturation of bioprinted excitable tissues. It addresses key limitations in physiological performance of bioprinted excitable tissues, outlines major stimulation modalities—including electrical, mechanical, optical, magnetic, ultrasound, and hybrid—and examines ...
Uijung Yong, Jinseon Park, Jinah Jang
wiley   +1 more source

Uncovering the mechanism of arecoline's effect on oral submucous fibrosis: integrating transcriptomics and <i>in vitro</i> and <i>in vivo</i> experiments. [PDF]

Front Physiol
Liu Z, Yi J, Zeng F, Chen B, Ning W, Tang J, OuYang Y.   +6 more
europepmc   +1 more source

Transcatheter Left Ventricular Restoration in Ischemic Heart Failure and Dilated Cardiomyopathy

Catheterization and Cardiovascular Interventions, Volume 107, Issue 4, Page 898-908, March 1, 2026.
ABSTRACT Ischemic heart disease is the leading global cause of death and frequently progresses to ischemic heart failure (IHF) after myocardial infarction through adverse left ventricular (LV)remodeling. Surgical LV restoration improves ventricular geometry and function but is limited by invasiveness and inconsistent outcomes.
Muhammad Mohid Haroon, Faizan Ahmad, Ramsha Ali, Saqlain Haider, Areehah Zafar Masood, Usama Yaseen, Taha Ahmad Zaka Ur Rehman, Muhammad Abdullah Sardar, Muhammad Umer, Shruthi Aswathappa, Muhammad Salman Sabri, Muhammad Muneeb Murtaza, Rubiya Ali, Sunny Kumar, Sameer Ali, Najam Gohar, Mohamed Bakr, Swapnil Patel, Mohammad A. Hussain, Fawaz Alenezi   +19 more
wiley   +1 more source

Transcription factor NRF2 and the expression of the Hippo pathway effector TAZ in bladder tumorigenesis are significantly correlated. [PDF]

Discov Oncol
Vahabirad M, Ghasemi H, Pegah A, Goli Z, Tavilani H.   +4 more
europepmc   +1 more source

CMA‐mediated USP9X degradation promotes SHH medulloblastoma progression by facilitating SUFU ubiquitination

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
Deubiquitinase USP9X suppresses SHH Medulloblastoma progression by facilitating SUFU ubiquitination. SHH promotes USP9X degradation through the CMA pathway. Combined inhibition of CMA and SHH pathway had a synergically therapeutic effect on SHH Medulloblastoma.
Binbin Gao, Qin Zhu, Lun Kuang, Jiahui Li, Qingyue Meng, Bo'ang Han, Yu Wang, Xinyi Zhang, Xiangxiang Zhang, Xinfa Wang, Tingting Yu, Shen Yue, Chen Liu   +12 more
wiley   +1 more source

Hippo signalling pathway mediates oncogenic properties of NAB2::STAT6 in solitary fibrous tumour. [PDF]

Cell Oncol (Dordr)
Salguero-Aranda C, Lobo-Selma L, Beltrán-Povea A, Baute-González S, Gilabert-Prieto P, Jordán-Perez C, Fernández-Juárez JA, Amaral AT, Rodríguez R, Díaz-Martín J, de Álava E.   +10 more
europepmc   +1 more source