Results 161 to 170 of about 22,844 (235)

The Contribution of Cholesterol and Squalene Synthase in Cancer: Molecular Mechanisms, Lipid Rafts and Therapeutic Approaches

Medicinal Research Reviews, Volume 46, Issue 2, Page 352-381, March 2026.
ABSTRACT A plethora of cellular signaling pathways are dysregulated in cancer cells, promoting carcinogenesis and migration. Cholesterol has recently been linked to cancer by several subcellular mechanisms, especially by its involvement in the formation of lipid rafts, which promote oncogenic signaling and cancer cell invasion. Squalene synthase (SQS),
Danai Mavridi, Theodora Katavati, Angeliki P. Kourounakis   +2 more
wiley   +1 more source

Recent advances on Hippo-YAP pathway in skin diseases. [PDF]

Front Immunol
Cai X, Chen K, Li X, Zhang K, Gu J, Shen C, Yu B, Huang C.   +7 more
europepmc   +1 more source

Targeting Tumor Dormancy and Recurrence: Molecular Mechanisms and Peptide Therapeutic Delivery

MedComm – Oncology, Volume 5, Issue 1, March 2026.
This review summarizes the molecular mechanisms that regulate tumor dormancy and its role in cancer recurrence, with emphasis on immune evasion, extracellular matrix remodeling, metabolic regulation and angiogenic switching. It further discusses emerging peptide–based therapeutic strategies aimed at detecting, modulating, and eliminating dormant tumor ...
Abdur Raheem Aleem, Atif Ali, Wajid Ali, Yuying Cheng, Zhibin Yan, Chaoyi Xia, Chenguang Liu, Caiyun Fu, Yiren Hu, Xi Wang   +9 more
wiley   +1 more source

Engineering Nanocellulose Scaffolds: Property Modification Strategies and Mechanotransduction‐Driven Tissue Outcomes

Polymers for Advanced Technologies, Volume 37, Issue 3, March 2026.
ABSTRACT Nanocellulose is being increasingly used in biomedical applications because of its biocompatibility, mechanical robustness, tunable surface chemistry, and adjustable rheology. This review evaluates recent strategies for engineering cellulose nanofibrils, nanocrystals, and bacterial nanocellulose into cell‐instructive scaffolds for skin, bone ...
Aurora Rodríguez Martínez, Aleida Nuñez Ruiz, Gloria Soldevila, Alejandro Elizalde Cárdenas, Guadalupe Antonio Ríos, Rosa María Ribas Aparicio, Maykel González Torres   +6 more
wiley   +1 more source

Cytomegalovirus Pneumonia Requiring Intensive Care During Treatment for Rapidly Progressive Interstitial Lung Disease Associated With Anti‐Synthetase Syndrome: A Case Report

Respirology Case Reports, Volume 14, Issue 3, March 2026.
We report a case of anti‐synthetase syndrome associated with rapidly progressive interstitial lung disease (RP‐ILD), complicated by early‐onset cytomegalovirus pneumonia that mimicked treatment‐resistant RP‐ILD on imaging. The patient survived intensive care and received antiviral therapy.
Hiroe Aramaki, Kiyomitsu Fukaguchi, Sachi Miyashita, Yuki Yao, Mizuki Sato, Shingo Ohki, Hiroshi Koyama, Satoshi Noma, Tomoya Fukui   +8 more
wiley   +1 more source

Platelet-Rich Plasma (PRP) bidirectionally modulates scar formation via the Piezo1-YAP/TAZ axis: a novel mechanotransduction hypothesis. [PDF]

Front Cell Dev Biol
Tian J, Yang J, Fu W, Cheng B.
europepmc   +1 more source

Functional polymer materials containing heavy group‐14 elements focusing on germanium and tin

Smart Molecules, Volume 4, Issue 1, March 2026.
The synthesis, functions, and applications of the polymers containing heavy group 14 elements focusing on germanium and tin are outlined. Owing to their large atomic radii and weak binding energies, the polymers show unique properties: chromism, luminescence, carrier mobility, and reactivity to produce radials and higher coordinated states.
Masayuki Gon, Kazuo Tanaka
wiley   +1 more source

Mechanosensitive Cell‐Laden Shape‐Memory Scaffolds Engineered via Cryogelation

Small Structures, Volume 7, Issue 3, March 2026.
GelMA‐based shape‐memory scaffolds encapsulating human adipose‐derived stem cells are fabricated via cryogelation, showing rapid recovery and high cell viability. Under cyclic compression, they promoted mechanotransduction gene expression, and composite formulations (collagen/GelMA, dECM/GelMA) retained robust shape‐memory, highlighting their promise ...
JaeYoon Lee, ByungJoon Choi, Hanjun Hwangbo, GaEun Heo, GeunHyung Kim   +4 more
wiley   +1 more source

Progress on the mechanism of Polycystin-1 in bone remodeling. [PDF]

Front Cell Dev Biol
Guo J, Hu G, Li X, Yi X, Chang B, Li T.
europepmc   +1 more source

Piezo1‐Mediated Mechanotransduction: Orchestrating the Dynamic Response of Podocytes and Parietal Epithelial Cells to Mechanical Stress

Acta Physiologica, Volume 242, Issue 3, March 2026.
ABSTRACT Aim The glomerulus is a specialized microvascular unit that filters plasma through the coordinated function of podocytes and parietal epithelial cells (PECs). From this perspective, the glomerulus functions like a living hydrogeological filtration system.
Maria Elena Melica, Giulia Antonelli, Anna Julie Peired, Laura Lasagni   +3 more
wiley   +1 more source