Results 171 to 180 of about 22,844 (235)
This study shows that YAP, a key effector of the Hippo pathway, is highly upregulated in glioblastoma and drives tumor growth, invasion, and survival. Knockdown of YAP or treatment with Resveratrol (a blood–brain barrier–permeable phytochemical) significantly reduced these malignant traits.
Wannawat Khotchawan +4 more
wiley +1 more source
LBPs NPs suppress breast cancer progression by inhibiting YAP1 expression to induce ferroptosis and alter energy metabolism. [PDF]
Zhao F +8 more
europepmc +1 more source
ABSTRACT Cellular SiC/thermoplastic polyurethane (TPU) components were printed via fused filament fabrication and impregnated with a commercial polysilazane. The pyrolysis process in an inert atmosphere converts the structure into a ceramic‐matrix composite through the polymer‐derived ceramics (PDCs) route.
Rajat Chaudhary +5 more
wiley +1 more source
In vitro evaluation of Verteporfin and exploration of TEAD palmitoylation inhibition in Piezo1-YAP/TAZ signaling and ECM remodeling. [PDF]
Xiaojun Z, Chen Q, Liu S, Liu B.
europepmc +1 more source
Alexidine is a TAZ-specific small-molecule inhibitor that suppresses breast cancer invasion and metastasis. [PDF]
Ge A +13 more
europepmc +1 more source
Inflammatory niches as spatial drivers of disease mechanisms and targets for personalized treatment
This study provides a comprehensive review of how spatial transcriptomics reveals disease‐specific inflammatory niches across multiple skin disorders, highlighting key immune–stromal, neuro–immune and metabolic interactions that were previously unappreciated in non‐spatial analyses. Abstract Disease states are increasingly recognized as being shaped by
Rundong Jiang +3 more
wiley +1 more source
A YAP/TAZ-CDC6 Axis Initiates and Maintains Malignant Transformation. [PDF]
Nduru D +5 more
europepmc +1 more source
ABSTRACT Early developmental processes significantly influence growth and maturation patterns, aquaculture traits that are critical for physiological adaptation and productivity. The vestigial‐like family member 3 gene (vgll3) plays a key role in growth and maturation across diverse taxa, including mammals and teleost fishes.
Aristotelis Moulistanos +6 more
wiley +1 more source

