Results 211 to 220 of about 104,199 (294)

The Molecular Exposome of Visible Age Reversal: From Organ-Skin Axes to Regenerative Aesthetics. [PDF]

Molecules
Yamada H.
europepmc   +1 more source

Targeted Therapy and Immunotherapies in Hepatocellular Carcinoma: Mechanisms and Clinical Studies

MedComm, Volume 7, Issue 5, May 2026.
The mechanism of multiple signaling pathways and their related targeted inhibitors in HCC. (A) The mechanism of Ras/Raf/MEK/ERK signaling pathway and its related targeted inhibitors; (B) the mechanism of PI3K/AKT/mTOR signaling pathway and its crosstalk with other pathways and its related targeted inhibitors; (C) the mechanism of JAK/STAT signaling ...
Penghui He, Sinan Xie, Kunlin Xie, Fengwei Gao, Yunshi Cai, Yan Huang, Chang Liu, Hong Wu, Yinghao Lyu, Tian Lan   +9 more
wiley   +1 more source

Hippo Pathway Drives Durable Non-Cell-Autonomous Ferroptosis Resistance in Lung Cancer. [PDF]

Cancer Sci
Saleh MF, Nita A, Ohta Y, Kobayashi A, Li H, Sakamoto Y, Moroishi T.   +6 more
europepmc   +1 more source

Carrier screening in the reproductive setting—Are there medical implications for the heterozygote?—A guide for clinicians

Pregnancy, Volume 2, Issue 3, May 2026.
Abstract Carrier screening for genetic conditions performed preconception or during pregnancy allows identification of fetal risk for inherited autosomal recessive and X‐linked conditions. The goal is to identify at‐risk patients/couples and offer them reproductive options such as preimplantation genetic diagnosis, prenatal testing, or targeted newborn
Emily B. Rosenfeld, Nicole Kasatkin, Bi Liu Yu, Milen Velinov, Justin S. Brandt, Elena Ashkinadze   +5 more
wiley   +1 more source

Mitochondrial Homeostasis in Pancreatic β Cell Function: Mechanisms and Therapeutic Targets for Diabetes

Journal of Diabetes, Volume 18, Issue 5, May 2026.
This review highlights mitochondrial dysfunction as a central driver of pancreatic β cell failure in diabetes, caused by disrupted mitochondrial quality control (MQC), oxidative stress, and impaired organelle communication. Emerging therapies, such as DRAK2 inhibitors and metabolic reprogramming agents, show promise in restoring β cell function by ...
Ruihan Li, Bingqian Zhang, Yuxin Zhang, Yang Yang, Yuting Lu, Jingya Li   +5 more
wiley   +1 more source

Critical threshold target attainment rates for tazobactam combined with piperacillin among patients admitted to the ICU with hospital-acquired pneumonia. [PDF]

Antimicrob Agents Chemother
Williamson R, Zurawska M, Valadez A, Harlan E, Scheetz MH, Neely MN, Yarnold PR, Kang M, Donnelly HK, Martinez F, Korth E, Medernach RL, Nozick SH, Hauser AR, Ozer EA, Diaz E, Misharin AV, Wunderink RG, Rhodes NJ.   +18 more
europepmc   +1 more source

Hcfc1 and Ogt Mediate Zebrafish CNS Regeneration Through Hippo/Yap Signalling

Cell Proliferation, Volume 59, Issue 5, May 2026.
This work identifies Hcfc1 and Ogt as key regulators of zebrafish CNS regeneration through modulation of Hippo/Yap signalling. Loss of Hcfc1 or Ogt activity inhibition impairs regeneration, which is restored by Yap overexpression, revealing a new regulatory axis that enhances CNS regenerative capacity.
Priyanka P. Srivastava, Sidharth Bhasin, Poonam Sharma, Omkar Mahadeo Desai, Kshitiz Yadav, Ayushma, Rohan Chakraborty, Suhel Parvez, Rajesh Ramachandran, Shilpi Minocha   +9 more
wiley   +1 more source

Erratum: Downregulation of MicroRNA-455-3p Links to Proliferation and Drug Resistance of Pancreatic Cancer Cells via Targeting TAZ. [PDF]

Mol Ther Nucleic Acids
Zhan T, Huang X, Tian X, Chen X, Ding Y, Luo H, Zhang Y.   +6 more
europepmc   +1 more source

Archivarstereotyp: Der taz-Archivar

Archivalia, 2007
openaire   +2 more sources

Mechanobiology in Stem Cell‐Based Bioprinting

Cell Proliferation, Volume 59, Issue 5, May 2026.
Mechanobiology in stem cell‐based bioprinting is an emerging field that bridges the mechanical conditions of the bioprinting process with the regulation of stem cell behaviour for engineering living tissues. Stresses encountered during bioprinting, together with the mechanical properties of bioinks, play a critical role in regulating stem cell ...
Supeng Ding, Tiankun Liu, Rui Yao
wiley   +1 more source