Results 211 to 220 of about 24,287 (262)

Mitochondrial membrane remodeling in stress adaptation: Lipid control of organelle quality

Protein Science, Volume 35, Issue 8, August 2026.
Abstract Mitochondria respond to proteotoxic stress through the mitochondrial unfolded protein response, traditionally viewed as a transcriptional program that restores proteostasis by inducing chaperones and proteases. Emerging evidence indicates that mitochondrial membrane remodeling constitutes an additional adaptive component of this response ...
Lena J. Reichert, F.‐Nora Vögtle, Carlotta Peselj   +2 more
wiley   +1 more source

Targeting BMP and TAZ/TEAD mechanotransduction pathways impairs acute myeloid leukemia chemoresistance. [PDF]

Leukemia
Barral L, Lespinasse N, Martin Cardozo C, Jeanpierre S, Bourgeois A, Rösel K, Beillard E, Laurent D, Peyrouze P, Belhabri A, Guillermin Y, Mazurier F, Cheok M, Audry-Deschamps MC, Faivre M, Maguer-Satta V, Lefort S.   +16 more
europepmc   +1 more source

3D Liver Fibrosis Models in Lab: A Novel Modality for Drug Screening

Pharmacology Research &Perspectives, Volume 14, Issue 4, August 2026.
ABSTRACT Liver fibrosis is the common consequence of liver injury caused by a variety of chronic liver disorders. This condition leads to the development of more severe complications, particularly cirrhosis and hepatocellular carcinoma. Despite abundant studies, the fundamental cell and molecular mechanisms of liver fibrosis are still unknown.
Hani Keshavarz Alikhani, Fatemeh Majidi, Mahsa Ghasemzad, Anastasia Shpichka, Anastasia Nestorova, Zahra Hendi, Elham Rismani, Daria Kuznetsova, Peter Timashev, Massoud Vosough, Abbas Piryaei   +10 more
wiley   +1 more source

Liver Stiffness Directs Intrahepatic Cholesterol Accumulation Through YAP/TAZ in Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Adv Sci (Weinh)
Lee NY, Choi MG, Ryu HJ, Min YJ, Kim SM, Chung Y, Koo BK, Kang YP, Kim W, Koo JH.   +9 more
europepmc   +1 more source

A Suspected Case of Allergic Bronchopulmonary Mycosis Associated With Exophiala dermatitidis

Respirology Case Reports, Volume 14, Issue 8, August 2026.
An 83‐year‐old man without asthma developed allergic bronchopulmonary mycosis (ABPM) associated with Exophiala dermatitidis. This case suggests that E. dermatitidis may be involved in ABPM. ABSTRACT Exophiala dermatitidis is a black fungus that can colonize the airways, but allergic bronchopulmonary mycosis (ABPM) associated with E.
Toshiyuki Yonezawa, Saori Onishi, Daisuke Sunakawa, Yasutaka Kato, Satoru Ito   +4 more
wiley   +1 more source

Hippo signaling differentially regulates distal progenitor subpopulations and their transitional states to construct the mammalian lungs. [PDF]

Nat Commun
Zhang K, Basak M, Zaher Y, Yao E, Wang SA, Aung T, Chuang PT.   +6 more
europepmc   +1 more source

Design and Fabrication of Complex Micro–Nano Structures for Osteogenesis Interfacing in 3D

Small Structures, Volume 7, Issue 8, August 2026.
The graphical abstract demonstrates the 3D Si structure platforms and the cell interactions. (left) Si structures including wine glass‐, obelisk‐, and pillar‐shaped structures are fabricated at wafer scale. (right) Compare to planar Si substrate, the wine glass‐shaped structures demonstrated promising cellular behavior and osteogenesis guidance by ...
Xuanrui Zhou, Yahui Pan, Thomas Grap, Sven Ingebrandt, Ziyu Gao   +4 more
wiley   +1 more source

PI3K regulates TAZ/YAP and mTORC1 axes that can be synergistically targeted. [PDF]

JCI Insight
Garcia KC, Khan AA, Ghosh K, Sinha S, Scalora N, DeWane G, Fullenkamp C, Merritt N, Drebot Y, Yu SY, Leidinger M, Henry MD, Breheny PJ, Chimenti MS, Tanas MR.   +14 more
europepmc   +1 more source

F2R and MXRA5: the metabolic obesity-derived biomarkers for immunosuppression and poor survival in triple-negative breast cancer. [PDF]

Discov Oncol
Li X, Wang Z, Huo X, Luo Y.
europepmc   +1 more source