Results 51 to 60 of about 37,775 (207)

A kinetic model of TBP auto-regulation exhibits bistability

open access: yesBiology Direct, 2010
Background TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA ...
Gokhale Sucheta A   +4 more
doaj   +1 more source

Hospitalizations for tuberculous peritonitis in the United States: Results from the national inpatient sample database from 2002 to 2014

open access: yesInternational Journal of Mycobacteriology, 2020
Background: Tuberculosis (TB) is an uncommon disease in the Western hemisphere that can present with peritoneal involvement, as tuberculous peritonitis(TBP) causing abdominal pain and fever.
Eric Martin Sieloff   +5 more
doaj   +1 more source

Human Engineered Heart Tissues Reproduce Trigger‐ and Substrate‐Driven Mechanisms of Ventricular Tachycardia

open access: yesAdvanced Science, EarlyView.
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler   +4 more
wiley   +1 more source

Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors [PDF]

open access: yesDevelopment, 2016
The developmental program relies on activating and repressing regulatory influences which are faithfully integrated at the core promoter of individual genes. In vertebrates, the basal machinery recognizing the core promoter includes TATA binding protein (TBP) and two TBP-related factors. In Xenopus embryos the three TBP family factors are all essential
Gazdag, E.   +4 more
openaire   +4 more sources

Chemical pretreatments of Trapa bispinosa's peel (TBP) biosorbent to enhance adsorption capacity for Pb(ll)

open access: yesOpen Chemistry, 2019
In this study, Trapa bispinosa's peel (TBP) biomass is exploited as an effective, low cost and new adsorbent to remove Pb(II) from aqueous solution.
Zafar Muhammad Nadeem   +5 more
doaj   +1 more source

Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens

open access: yesAdvanced Science, EarlyView.
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu   +12 more
wiley   +1 more source

Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus [PDF]

open access: yesScience, 2000
The TATA-binding protein (TBP) is believed to function as a key component of the general transcription machinery. We tested the role of TBP during the onset of embryonic transcription by antisense oligonucleotide–mediated turnover of maternal TBP messenger RNA.
Weeks, D.L.   +2 more
openaire   +3 more sources

Improved anti-corrosion performance of epoxy coatings based on pH-sensitive gels loaded with inhibitors

open access: yesJournal of Materials Research and Technology
The pH-sensitive Tannic acid@ Benzotriazole@ Poly (hydroxypropyl acrylate-triethoxyvinylsilane -acrylic acid)/polyethyl enimide (TBP) gels loaded with corrosion inhibitors and the modified TBP composite coatings (TBP/EP coatings) were prepared ...
Bo Fang   +8 more
doaj   +1 more source

Optimizing Electrode Design for Functional Activation of Human Pluripotent Stem Cell‐Derived Cardiomyocytes

open access: yesAdvanced NanoBiomed Research, EarlyView.
Electrical stimulation of human pluripotent stem cell‐derived cardiomyocytes is systematically investigated as a function of electrode material and configuration. Stimulation efficiency is found to be governed predominantly by electrode geometry, with increased electrode area and proximity to cells enabling more effective pacing.
Gustavo Ramirez‐Calderon   +12 more
wiley   +1 more source

Identification of a mouse TBP-like protein (TLP) distantly related to the Drosophila TBP-related factor [PDF]

open access: yesNucleic Acids Research, 1999
TATA-binding protein (TBP) is an essential factor for eukaryotic transcription. In this study, we demonstrated a mouse cDNA encoding a 21 kDa TBP-like protein (TLP). The TLP ORF, carrying 186 amino acids, covered the entire 180 amino acids of the C-terminal conserved domain of mouse TBP with 39% identity and 76% similarity.
T, Ohbayashi, Y, Makino, T A, Tamura
openaire   +2 more sources

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