Results 51 to 60 of about 37,775 (207)
A kinetic model of TBP auto-regulation exhibits bistability
Background TATA Binding Protein (TBP) is required for transcription initiation by all three eukaryotic RNA polymerases. It participates in transcriptional initiation at the majority of eukaryotic gene promoters, either by direct association to the TATA ...
Gokhale Sucheta A +4 more
doaj +1 more source
Background: Tuberculosis (TB) is an uncommon disease in the Western hemisphere that can present with peritoneal involvement, as tuberculous peritonitis(TBP) causing abdominal pain and fever.
Eric Martin Sieloff +5 more
doaj +1 more source
Engineered heart tissues (EHTs) derived from human iPSCs replicate mechanisms of ventricular tachycardia at the tissue level. Acquired Long‐QT conditions cause early afterdepolarizations, wavebreak, and transient rotors; in contrast, focal cryoinjury forms a stable substrate that supports ongoing reentry.
Matthew Fiedler +4 more
wiley +1 more source
Activation of a T-box-Otx2-Gsc gene network independent of TBP and TBP-related factors [PDF]
The developmental program relies on activating and repressing regulatory influences which are faithfully integrated at the core promoter of individual genes. In vertebrates, the basal machinery recognizing the core promoter includes TATA binding protein (TBP) and two TBP-related factors. In Xenopus embryos the three TBP family factors are all essential
Gazdag, E. +4 more
openaire +4 more sources
In this study, Trapa bispinosa's peel (TBP) biomass is exploited as an effective, low cost and new adsorbent to remove Pb(II) from aqueous solution.
Zafar Muhammad Nadeem +5 more
doaj +1 more source
Single‐Nucleus RNA Sequencing Identifies CREM as a Brake on Myofiber Hypertrophy in Chickens
Single‐nucleus RNA sequencing on 91 144 nuclei from postnatal chicken pectoralis major between fast‐growing broilers (FG) and slow‐growing layers (SG) identifies the transcriptional factor CREM as a novel brake of myofiber hypertrophy. Mechanistically, functional validation experiments confirm that CREM activates the promoter of JUN and CREM deletion ...
Shuang Gu +12 more
wiley +1 more source
Distinct Roles for TBP and TBP-Like Factor in Early Embryonic Gene Transcription in Xenopus [PDF]
The TATA-binding protein (TBP) is believed to function as a key component of the general transcription machinery. We tested the role of TBP during the onset of embryonic transcription by antisense oligonucleotide–mediated turnover of maternal TBP messenger RNA.
Weeks, D.L. +2 more
openaire +3 more sources
The pH-sensitive Tannic acid@ Benzotriazole@ Poly (hydroxypropyl acrylate-triethoxyvinylsilane -acrylic acid)/polyethyl enimide (TBP) gels loaded with corrosion inhibitors and the modified TBP composite coatings (TBP/EP coatings) were prepared ...
Bo Fang +8 more
doaj +1 more source
Electrical stimulation of human pluripotent stem cell‐derived cardiomyocytes is systematically investigated as a function of electrode material and configuration. Stimulation efficiency is found to be governed predominantly by electrode geometry, with increased electrode area and proximity to cells enabling more effective pacing.
Gustavo Ramirez‐Calderon +12 more
wiley +1 more source
Identification of a mouse TBP-like protein (TLP) distantly related to the Drosophila TBP-related factor [PDF]
TATA-binding protein (TBP) is an essential factor for eukaryotic transcription. In this study, we demonstrated a mouse cDNA encoding a 21 kDa TBP-like protein (TLP). The TLP ORF, carrying 186 amino acids, covered the entire 180 amino acids of the C-terminal conserved domain of mouse TBP with 39% identity and 76% similarity.
T, Ohbayashi, Y, Makino, T A, Tamura
openaire +2 more sources

