Results 61 to 70 of about 44,938 (289)

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID

open access: yeseLife, 2017
General transcription factor TFIID is a key component of RNA polymerase II transcription initiation. Human TFIID is a megadalton-sized complex comprising TATA-binding protein (TBP) and 13 TBP-associated factors (TAFs).
Kapil Gupta   +20 more
doaj   +1 more source

Atomic structure of the SAGA complex and it’s interaction with TBP

open access: yesComptes Rendus Biologies, 2021
The transcription of eukaryotic protein genes is controlled by a plethora of proteins which act together in multi-component complexes to facilitate the DNA dependent RNA polymerase II (Pol II) enzyme to bind to the transcription start site and to ...
Papai, Gabor   +5 more
doaj   +1 more source

New AI‐Assisted Approach for Expanding the Solution Space: Application to Lattice Structure Design

open access: yesAdvanced Engineering Materials, EarlyView.
This work introduces an innovative framework for designing structured materials by ex panding the design space through reparameterization of qualitative variables into continuous structural descriptors. Combined with machine‐learning‐based prediction and multi‐objective optimization, the approach enables the discovery of novel lattice architectures ...
G. H. Gahimbare   +5 more
wiley   +1 more source

Deactivation of TBP contributes to SCA17 pathogenesis [PDF]

open access: yes, 2020
Spinocerebellar ataxia type 17 (SCA17) is an autosomal dominant cerebellar ataxia caused by the expansion of polyglutamine (polyQ) within the TATA box-binding protein (TBP).
Guey-Jen Lee-Chen   +8 more
core  

Scavenging of stored TBP waste [PDF]

open access: yes, 1955
The reactivation of B-Plant and the continued operation of T-Plant under the 4X Program have led to the problem of obtaining additional underground tankage in both 200 East Area and 200 West Area for the storage of B-Plant metal waste, second cycle waste
Ingalls, W. P., Poucher, F. W.
core   +1 more source

Spiro‐Phenothiazine Hole‐Transporting Materials: Unlocking Stability and Scalability in Perovskite Solar Cells

open access: yesAdvanced Materials, EarlyView.
Fluorene‐functionalized spiro‐phenothiazine (PTZ‐Fl) exhibits strong Li+ affinity and thermal stability, enabling a PCE of 25.75% in small‐area cells and 22.07% in 25 cm2 modules. Under ISOS‐L3 conditions, PTZ‐Flbased devices retain over 80% efficiency after 1000 hours, demonstrating superior stability and scalability compared to spiro‐OMeTAD for next ...
Javier Urieta‐Mora   +17 more
wiley   +1 more source

A regulated two-step mechanism of TBP binding to DNA: A solvent-exposed surface of TBP inhibits TATA box recognition [PDF]

open access: yes, 2002
The TATA box binding protein TBP plays a universally important role in eukaryotic nuclear transcription. By mutagenesis, we have discovered a solvent-exposed surface of the structured TBP core domain that is important for inhibition of the DNA binding ...
Herr, Winship   +3 more
core   +1 more source

Closed‐Loop Recyclable Solid Polymer Electrolytes via Dynamic Lipoate Cross‐Linking

open access: yesAngewandte Chemie, EarlyView.
A visible‐light‐driven, closed‐loop recyclable solid polymer electrolyte is built from a bio‐derived lipoate cross‐linker, poly(ethylene glycol) bis(lipoate) (PEG‐LP2), synthesized from α‐lipoic acid. Dynamic disulfide exchange enables efficient DBU‐catalyzed depolymerization and photo‐repolymerization, regenerating membranes that retain high ionic ...
Qian Huang   +6 more
wiley   +2 more sources

Evolutionary history of the TBP-domain superfamily [PDF]

open access: yesNucleic Acids Research, 2013
The TATA binding protein (TBP) is an essential transcription initiation factor in Archaea and Eucarya. Bacteria lack TBP, and instead use sigma factors for transcription initiation. TBP has a symmetric structure comprising two repeated TBP domains.
Brindefalk, Björn   +5 more
openaire   +2 more sources

Evidence for Itinerant Ferromagnetic Flat Bands Producing Large Transverse Responses

open access: yesAdvanced Materials, EarlyView.
Itinerant ferromagnetic flat bands are demonstrated in GdCo5 with a high Curie temperature of 940K, a stacked honeycomb–kagome lattice, through angle‐resolved photoemission spectroscopy and magneto‐thermoelectric measurements. These topological flat bands generate large Berry curvaturte, producing gigantic anomalous Nernst effect with record‐high ...
Susumu Minami   +15 more
wiley   +1 more source

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