Results 51 to 60 of about 249,034 (202)

Multistationary and Oscillatory Modes of Free Radicals Generation by the Mitochondrial Respiratory Chain Revealed by a Bifurcation Analysis [PDF]

open access: yes, 2012
The mitochondrial electron transport chain transforms energy satisfying cellular demand and generates reactive oxygen species (ROS) that act as metabolic signals or destructive factors.
Mark F. Schumaker   +6 more
core   +5 more sources

Mitochondrial metabolism in TCA cycle mutant cancer cells [PDF]

open access: yesCell Cycle, 2013
Normal cells and cancer cells rely on mitochondria for a range of essential functions including production of ATP, biosynthetic intermediates, heme and iron-sulfur clusters, and reactive oxygen species (ROS) for signaling. These functions are essential for cell survival and proliferation.
Sullivan, Lucas B, Chandel, Navdeep S
openaire   +2 more sources

Fuelling of TCA cycle in hepatic cells Marwari goat during ambient temperature associated stress [PDF]

open access: yes, 2010
The present study was launched to assess the effect of extreme ambient temperature associated stress on fuelling of TCA cycle in hepatic cells of Marwari goat.
Joshi A., Kataria A.K., Kataria N.
core  

Edwardsiella tarda Tunes Tricarboxylic Acid Cycle to Evade Complement-Mediated Killing

open access: yesFrontiers in Immunology, 2017
Evasion of complement-mediated killing is a common phenotype for many different types of pathogens, but the mechanism is still poorly understood. Most of the clinic isolates of Edwardsiella tarda, an important pathogen infecting both of human and fish ...
Zhi-xue Cheng   +10 more
doaj   +1 more source

Global isoform-specific transcript alterations and deregulated networks in clear cell renal cell carcinoma. [PDF]

open access: yes, 2018
Extensive genome-wide analyses of deregulated gene expression have now been performed for many types of cancer. However, most studies have focused on deregulation at the gene-level, which may overlook the alterations of specific transcripts for a given ...
Girke, Thomas   +2 more
core   +1 more source

The Tricarboxylic Acid Cycle Metabolites for Cancer: Friend or Enemy

open access: yesResearch
The tricarboxylic acid (TCA) cycle is capable of providing sufficient energy for the physiological activities under aerobic conditions. Although tumor metabolic reprogramming places aerobic glycolysis in a dominant position, the TCA cycle remains ...
Jie Wu   +7 more
doaj   +1 more source

The impact of RNA binding proteins and the associated long non-coding RNAs in the TCA cycle on cancer pathogenesis

open access: yesRNA Biology, 2023
The tricarboxylic acid (TCA) cycle is a central route for generating cellular energy and precursors for biosynthetic pathways. Emerging evidences have shown that the aberrations of metabolic enzymes which affect the integrity of TCA cycle are implicated ...
Tao Shen   +4 more
doaj   +1 more source

Alteration of the interconversion of pyruvate and malate in the plastid or cytosol of ripening tomato fruit invokes diverse consequences on sugar but similar effects on cellular organic Acid, metabolism, and transitory starch accumulation

open access: yes, 2013
The aim of this work was to investigate the effect of decreased cytosolic phosphoenolpyruvate carboxykinase (PEPCK) and plastidic NADP-dependent malic enzyme (NADP-ME) on tomato (Solanum lycopersicum) ripening.
Angelovici, R.   +7 more
core   +1 more source

The cell cycle program of polypeptide labeling in Chlamydomonas reinhardtii [PDF]

open access: yes, 1977
The cell cycle program of polypeptide labeling in syndhronous cultures of wild-type Chlamydomonas reinhardtii was analyzed by pulse-labeling cells with 35SO4 = or [3H]arginine at different cell cycle stages.
Hill, Kim R.   +2 more
core   +5 more sources

Effects of citric acid on antioxidant system and carbon-nitrogen metabolism of Elymus dahuricus under Cd stress

open access: yesEcotoxicology and Environmental Safety, 2022
Exogenous citric acid (CA), which acts as an important intermediate product of the tricarboxylic acid (TCA) cycle, can enhance the TCA cycle activity and activate the branched operation of the TCA cycle, thus providing energy required for resistance to ...
Zhehan Yang   +3 more
doaj   +1 more source

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