Results 11 to 20 of about 7,461 (172)

Evaluating the carcinogenic potential and molecular mechanisms of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the human stomach using organoids and bulk sequencing data: a multi-machine learning approach combined with computational simulation [PDF]

Discover Oncology
Objective This study investigates the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on the pathogenesis of gastric cancer and its associated molecular mechanisms, particularly the interaction between TCDD and key targets and pathways.
Youfu Tian, Dede Ma, Ke Yan, Bing Xiao, Jie Liu, Miao Tan   +5 more
doaj   +2 more sources

TCDD promotes lung tumors via attenuation of apoptosis through activation of the Akt and ERK1/2 signaling pathways. [PDF]

PLoS ONE, 2014
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a multiple-site, multiple-species carcinogen that induces cancer in multiple organs. The molecular mechanisms underlying TCDD-induced lung tumorigenesis remain unclear.
Rong-Jane Chen, Shih-He Siao, Chung-Huei Hsu, Chu-Yung Chang, Louis W Chang, Chih-Hsiung Wu, Pinpin Lin, Ying-Jan Wang   +7 more
doaj   +1 more source

MODIFIED SNODGRASS TECHNIQUE IN DISTAL HYPOSPADIAS

Urology Research and Practice, 2019
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A. METİN, Ö. KAYIGİL, S.İ. AHMED
doaj   +2 more sources

Transcriptional, hormonal and histological alterations in the ovaries of BALB/c mice exposed to TCDD in connection with multigenerational female infertility

Ecotoxicology and Environmental Safety, 2023
2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), the most toxic congener of dioxins, has a proven reproductive toxicity. Due to the lack of evidence on the multigenerational female reproductive toxicity of TCDD through the maternal exposure, the current study
Nour Aldeli, Chadi Soukkarie, Abdulsamie Hanano   +2 more
doaj   +1 more source

OUR SURGICAL RESULTS IN PENILE CURVATURE

Urology Research and Practice, 2019
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A. METİN, Ö. KAYIGİL, S.İ. AHMED
doaj   +2 more sources

Effect of TCDD exposure in adult female and male mice on the expression of miRNA in the ovaries and testes and associated reproductive functions

Frontiers in Toxicology, 2023
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is an environmental contaminant found widely across the world. While animal and human studies have shown that exposure to TCDD may cause significant alterations in the reproductive tract, the effect of TCDD on ...
Alina Hall, Donald Mattison, Narendra Singh, Ioulia Chatzistamou, Jiajia Zhang, Mitzi Nagarkatti, Prakash Nagarkatti   +6 more
doaj   +1 more source

BLADDER NECK SUSPENSION VERSUS MODIFIED INSITU VAGINAL WALL SLING IN STRESS INCONTINENCE

Urology Research and Practice, 2019
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A. METİN, Ö. KAYIGİL, S.İ. AHMED
doaj   +2 more sources

Prenatal dioxin exposure and glucose metabolism in the Seveso Second Generation study

Environment International, 2020
Background: Exposure to endocrine disrupting compounds such as 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) during susceptible developmental windows may alter risk of metabolic disease later in life. Animal studies of in utero and lactational TCDD exposure
Marcella Warner, Stephen Rauch, Paolo Brambilla, Stefano Signorini, Paolo Mocarelli, Brenda Eskenazi   +5 more
doaj   +1 more source

RETROSPECTIVE EVALUATION OF 42 PATIENTS WITH URETHRAL STRICTURE WHO WERE FOLLOWED AT OUR CLINIC

Urology Research and Practice, 2019
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Ö. ATAHAN, Ö. KAYIGİL, A. METİN
doaj   +2 more sources

Effect Of Alpha-Tocopherol On Spermatozoa Death Of Apoptosis and Necrosis in Rats (Rattus Norvegicus) Exposed 2,3,7,8- Tetrachlorodibenzo-P-Dioxin

Journal of Stem Cell Research and Tissue Engineering, 2021
The aims of this research was to investigate effect of alpha-tocopherol on spermatozoa death in form of apoptosis and necrosis in rats (Rattus norvegicus) exposed 2,3,7,8- tetrachlorodibenzo-p-dioxin. Male rats were administered TCDD and alpha-tocopherol
Valderama Gomang
doaj   +1 more source