Results 171 to 180 of about 146,987 (295)

A full-automated tumor budding annotation approach in hematoxylin and eosin-stained whole slide images of colorectal cancer. [PDF]

NPJ Precis Oncol
Peng S, Chang X, Luo Y, Tang H, Yang M, Zhong C, Deng C, Hao S, Jin Y, Li M, Bai X, Nie X.   +11 more
europepmc   +1 more source

FRA-RIG LUNG Cancer (TCGA-LUAD, sklearn demo): survival risk models

AdmailFRA
openalex   +1 more source

Integration of scRNA-Seq and TCGA RNA-Seq to Analyze the Heterogeneity of HPV+ and HPV- Cervical Cancer Immune Cells and Establish Molecular Risk Models

, 2022
Erdong Wei, Amin Reisinger, Jiahua Li, Lars E. French, Benjamin M. Clanner‐Engelshofen, Markus Reinholz   +5 more
openalex   +1 more source

The KDM6B/SLC10A2 Axis Suppresses MDSCs Recruitment via ERK/AP‐1 Signaling in Colorectal Cancer

Advanced Science, EarlyView.
In wild‐type intestinal epithelial cells, KDM6B demethylates SLC10A2 to promote its expression, after which SLC10A2 suppresses ERK phosphorylation, inhibiting AP‐1 (Fos/Jun) transcription and chemokine production. In KDM6B‐deficient intestinal epithelial cells, SLC10A2 methylation increases, and its expression decreases.
Zhibo Hu, Jing Xun, Bin Liu, Xiaolin Jiang, Yingdi Han, Huichao Yang, Qi Gao, Ruifang Gao, Aimin Zhang, Xueliang Wu, Dapeng Zhang, Dihua Li, Tian Li, Shimin Yang, Ximo Wang, Xiangyang Yu, Qi Zhang   +16 more
wiley   +1 more source

AGR2 suppresses ferroptosis via the p53/FPN1 regulatory axis and drives therapeutic vulnerabilities in pancreatic cancer. [PDF]

Cell Death Dis
Jian Z, Song J, Lu L, Pan T, Zhang H, Zhang Q, Zhang W, Li R, Gong J, Shi N, Zuo S, Cheng T, Yang Y, Zhang Z.   +13 more
europepmc   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Expression and association of HNRNPA2B1 with clinical prognosis in breast cancer: An evaluation based on the TCGA and GEO databases. [PDF]

Medicine (Baltimore)
Yi L, Wang H, Lei H.
europepmc   +1 more source

Spatio‐Temporal Proteomic Landscape Reveals Early Warning Signals of Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
This study constructs a proteomic atlas of esophageal squamous cell carcinoma (ESCC) progression using esophageal biopsy samples. It identifies moderate dysplasia as the critical turning stage and a seven‐protein panel for early detection. Functionally, GBP6 loss promotes ESCC progression via cell cycle and epithelial‐mesenchymal transition (EMT ...
Xumiao Li, Jie Yuan, Min Gao, Jibin Liu, Qinqin Wang, Yaqi Zhang, Mingtao Cao, Xiaolin Hu, Hui Yang, Jun Li, Chen Li, Xiaoguang Li, Hui Wang   +12 more
wiley   +1 more source

Multimodal deep learning for cancer prognosis prediction with clinical information prompts integration. [PDF]

NPJ Digit Med
Hou J, Zhang R, Xie Y, Li C, Qin W.
europepmc   +1 more source

Clinical features of GC patients in the TCGA dataset.

Changqi Du (21696596), Shuang Liang (211832), Xia Wang (36364), Yujiao Qi (329889), Shangdong Li (11880235), Hongling Li (1500382)   +5 more
openalex   +1 more source