Results 211 to 220 of about 146,987 (295)

Predicting the influence of homologous recombination repair deficiency genes on glioma heterogeneity and patient prognosis using multi-omics analysis and machine learning. [PDF]

PLoS One
Wu X, Li L, Zhan Z, Chang M, Li J, Chen Z, Wang Z.   +6 more
europepmc   +1 more source

Targeting IL27RA Enhances Immunotherapy in Triple‐Negative Breast Cancer by Modulating Tumor Cells and the Tumor Microenvironment

Advanced Science, EarlyView.
IL27RA upregulation drives immune evasion in TNBC by suppressing MHC‐I expression and reprogramming T/NK‐cell states, establishing an immune‐excluded tumor phenotype. Targeting this epithelial‐intrinsic IL27RA–PI3K/AKT axis offers a promising strategy to overcome immunotherapy resistance.
Jiachi Xu, Qian Long, Meirong Zhou, Qitong Chen, Jing Peng, Qingchun Liang, Danhua Zhang, Hui Zhou, Wenjun Yi   +8 more
wiley   +1 more source

Recent Updates on PRDM2 in Colorectal Cancer

Frontiers in Bioscience-Landmark
Erika Di Zazzo, Monica Rienzo, Amelia Casamassimi, Patrizia Gazzerro, Ciro Abbondanza   +4 more
doaj   +1 more source

High expression of TRMT112 is associated with the development of oral squamous cell carcinoma. [PDF]

J Oral Biol Craniofac Res
Pandi A, Rajendhiran P, Jayaseelan VP, Arumugam P.   +3 more
europepmc   +1 more source

TCGA-COMBINED_CAMDA_SyntheticDataset_e-10

Shane Menzies, Sikha Pentyala
openalex   +1 more source

73P TROP2 amplification is highly present in dedifferentiated liposarcoma: Data from the Cancer Genome Atlas (TCGA) in soft tissue sarcoma [PDF]

Sonia Maria Orlando, Simcha Pollack, Antonio Mazzocca, Carolyn Moloney, Ferdinando Paternostro, L. Ambrogioni, D. Romandini, B. Vincenzi, Pedro Viveiros   +8 more
openalex   +1 more source

Core Fucosylation Represses SMURF1‐Dependent Degradation of CD47 to Promote Tumor Immune Evasion

Advanced Science, EarlyView.
FUT8‐mediated core fucosylation of CD47 at N111 blocks SMURF1 binding and reduces CD47 ubiquitination and degradation. Blocking N111 glycosylation reduces CD47 expression and promotes macrophage phagocytosis of tumor cells. Furthermore, ablating CD47 core fucosylation boosts CD103+ dendritic cells (DCs) infiltration, increases natural killer (NK) cell ...
Yuting Cao, Siyuan Chai, Mingyang Li, Xiaoming Chen, Jiating Hu, Bingyi Lin, Liming Wu, Wen Yi, Qiang Zhu   +8 more
wiley   +1 more source

Integrative multi-omics and machine learning framework identifies PRDX4 as a redox-EMT regulator and predictive marker in bone-metastatic breast cancer. [PDF]

NPJ Precis Oncol
Zhou X, Xie L, Liu J, Liao G, Yang H.
europepmc   +1 more source

Deceptive Bias Measurement in Deep Learning: Assessing Shortcut Reliance in TCGA Cancer Models [PDF]

Farnaz Kheiri, Shahryar Rahnamayan, Masoud Makrehchi   +2 more
openalex   +1 more source

TCGA data reveal a highly heterogeneous disease [PDF]

Nature Reviews Clinical Oncology, 2017
openaire   +1 more source