Results 51 to 60 of about 197,260 (304)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Fer-1 like family member 4 pseudogene
EXCLI Journal : Experimental and Clinical SciencesCutaneous melanoma is the deadliest form of skin cancer. Despite advancements in treatment, many patients still face poor outcomes. A deeper understanding of the mechanisms involved in melanoma pathogenesis is crucial for improving diagnosis and therapy.
Tomasz Kolenda +15 more
doaj +1 more source
Cells, 2020 Epstein−Barr virus (EBV) is responsible for approximately 9% of stomach adenocarcinomas. EBV-encoded microRNAs have been reported as reducing the function of the class I major histocompatibility complex (MHC-I) antigen presentation apparatus, which
Farhad Ghasemi +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
The TCGA Meta-Dataset Clinical Benchmark
CoRR, 2019 5 Pages, Submitted to MLCB ...
Mandana Samiei +8 more
openaire +3 more sources
Cancer Management and Research, 2020 Zheng Li,* Ci Yin,* Bin Li, Qi-Yao Yu, Wen-Jie Mao, Jie Li, Jun-Ping Lin, Yu-Qi Meng, Hai-Ming Feng, Tao Jing Department of Thoracic Surgery, Lanzhou University Second Hospital, Lanzhou University Second Clinical Medical College, Lanzhou 730030, China ...
Li Z +9 more
doaj
The diagnostic and prognostic value of C1orf174 in colorectal cancer [PDF]
BioImpactsIntroduction: Colorectal cancer (CRC) is among the lethal cancers, indicating the need for the identification of novel biomarkers for the detection of patients in earlier stages.
Elham Nazari +18 more
doaj +1 more source
Identification of an immune-related signature for the prognosis of uveal melanoma [PDF]
International Journal of Ophthalmology, 2020 "AIM: To construct an immune-related prognostic signature (IPS) that can distinguish and predict prognosis in uveal melanoma (UM). METHODS: The transcriptomic data and clinicopathological information of 80 UM patients were extracted from the TCGA ...
Ying-Zi Li +3 more
doaj +1 more source
JomaMinoza/TCGA-Cancer-Data-Preparation v0.1-alpha
, 2020 Data Preparation Scripts for Extracting RNASeq and Clinical Data from TCGA Cancer ...
Jose Marie Antonio Minoza
core +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source