Results 191 to 200 of about 156,157 (263)

An Exercise‐Pollution Exposure Index for Assessing Inhaled Heavy Metal Exposure Along Urban Walking Routes

Environmental Toxicology, EarlyView.
ABSTRACT Urban walking routes are promoted as health‐supportive environments, yet they may also act as microenvironments of pollutant exposure during physical activity. This study evaluated heavy metal exposure along urban walking routes by integrating road dust metal concentrations, conventional health risk assessment, deposited inhalation dose, and ...
Berfin Sever, Hülya Aykaç Özen, Nurgül Yiğit Dönmez   +2 more
wiley   +1 more source

Discovery of Post-Translationally Modified Epitopes in Autoimmunity: Someone Has to Fish so Everyone Can Eat. [PDF]

Immunol Rev
Arshad S, Cameron BM, Joglekar AV.
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Nanomedicine applications in lymphoma: Advancing precision diagnostics, targeted therapeutics, and prospective developments

VIEW, EarlyView.
Lymphoma is a group of blood cancers that can appear in lymph nodes, blood, bone marrow, spleen, liver, or the central nervous system, which makes drug delivery and disease monitoring difficult. This review summarizes how nanomedicine technologies may improve targeted treatment and imaging, while carefully separating approved or guideline‐supported ...
Mohd Ahmar Rauf, Yara Mashal, Afeefa Rao, Nasar Ata, Arun K. Iyer, Farhan Shah   +5 more
wiley   +1 more source

Bridging model performance and clinical utility in T cell receptor-epitope binding prediction. [PDF]

Clin Transl Med
Wang Y, Lu Y, Suo S.
europepmc   +1 more source

Predicting specificity of TCR-pMHC interactions using machine-learning and biophysical models. [PDF]

Cell Syst
Culka M, Lounsbury NW, Thrift W, Nerli S, Wallace A, Nikolényi G, Orlova D, Mukhyala K, AlQuraishi M.   +8 more
europepmc   +1 more source

Carbamazepine activates private self and viral reactive TCRs through a drug-permissive HLA-B cleft. [PDF]

Front Immunol
Hwang S, Yano M, Jang Y, Khalaj M, Mattson E, Lu L, Kortchak S, Gorman J, Puig M, Norcross M.   +9 more
europepmc   +1 more source