Results 101 to 110 of about 95,928 (301)

A Personalized Haplotype‐Resolved Near‐Gapless Genome Framework for Somatic Variant Discovery in Hepatocellular Carcinoma

Advanced Science, EarlyView.
A patient‐specific, haplotype‐resolved genome framework improves detection and interpretation of somatic variants in hepatocellular carcinoma. Using multi‐platform sequencing, the personalized assembly resolves complex regions including centromeres and MHC/HLA loci, enhances structural variant discovery, and links regulatory alterations to allele ...
Jiazheng Lin, Yao Xiao, Shuangzi Luo, Yifan Li, Wenfei Zhang, Xiaoyu Zhang, Xinyi Wang, Di Wu, Jieru Hong, Yongkun Luan, Xun Huang, Yixiu Wang, Ningbo Wu, Xiaoxiao Hu, Fei Zhao, Wei Li, Xiao Luo, Bi Shi   +17 more
wiley   +1 more source

Barriers to Integrating Tobacco Dependence Treatment into Lung Cancer Screening: A Qualitative Assessment

Journal of Primary Care & Community Health
Introduction/objective: We qualitatively assessed current practices and perceived barriers surrounding the integration of tobacco dependence treatment (TDT) into lung cancer screening (LCS).
Deborah L. Pestka, Megan E. Campbell, Naomi A. Schmulewitz, Anne C. Melzer   +3 more
doaj   +1 more source

Nanoparticle‐Mediated Bubble Suppression During Droplet Solidification for Mechanical Reinforcement

Advanced Science, EarlyView.
Nanoparticles mediate droplet solidification by raising nucleation temperature, refining dendrites, and slowing freezing‐front advance, thereby suppressing trapped air bubbles in droplet‐based 3D printing. This strategy reduces bubble volume fraction by ∼35% and increases compressive strength by up to 39%, offering a low‐cost route to stronger printed ...
Runmiao Gao, Xuan Zhang, Mengjie Song, Ronggui Yang, Keke Shao, Jun Shen, Long Zhang, Shuhuai Yao, Yubing Guo, Ruzhu Wang, Christopher Yu Hang Chao   +10 more
wiley   +1 more source

Deviations within different subdomains (except within Loop1) observed in TdT-short and long isoform.

, 2016
RMSD of subdomains of TdT-short and TdT-long for simulations runs at 311 K for 100 ns. Index: TdT-short (run1: black, run2: red), TdT-long form (run1: green, run2: blue).
Ramanathan Sowdhamini (5068), Eshita Mutt (378233)   +1 more
core   +1 more source

Receptogenesis in a Vascularized Robotic Embodiment

Advanced Science, EarlyView.
Functional augmentation of situated robots via ex novo hardware generation extends physical adaptability. Drawing inspiration from open circulatory systems for mass and function redistribution, this study presents a vascularized robotic composite exhibiting receptogenesis ‐ the on‐demand construction of sensors ‐ from internal fluid reserves based on ...
Kadri‐Ann Pankratov, Leonid Zinatullin, Hans Priks, Adele Metsniit, Urmas Johanson, Tarmo Tamm, Alvo Aabloo, Edoardo Sinibaldi, Indrek Must   +8 more
wiley   +1 more source

TdT ubiquitylation in vivo or in vitro.

, 2012
(A) Endogenous TdT ubiquitylation in Jurkat cells. Immunoprecipitation was carried out using an anti-TdT antibody (lanes 4 and 6) or rabbit pre-immune serum (pre-IS) (lanes 3 and 5).
Takuro Matsumoto (152830), Tomoyoshi Kato (152813), Sachiko Ando (152827), So Maezawa (152806), Kotaro Koiwai (152844), Osamu Koiwai (152848), Takahide Hayano (152836), Masahiro Suzuki (152839), Yoshihiro Nishiyama (152821), Rie Fukushima (152809), Toyofumi Matsushita (152811), Yoshiki Takagaki (152817), Kousuke Kouda (152833)   +12 more
core   +1 more source

A Microcapsule‐Integrated smRandom‐seq Platform Enables Fixation‐Free Single Microbe RNA Sequencing

Advanced Science, EarlyView.
We developed a microcapsule‐integrated high‐throughput fixation‐free single‐microbe RNA‐seq workflow in which microbes are encapsulated in aqueous two‐phase microcapsules for physical confinement of nucleic acids. This platform enables co‐encapsulation with barcoded beads for sequencing and reveals that fixation‐free processing enhances transcriptomic ...
Mengdi Song, Yuting Wang, Zhaolun Wang, Shunji Zhang, Zhengmin Tang, Yongcheng Wang   +5 more
wiley   +1 more source

Effect of Tdt on meganuclease-induced mutagenesis.

, 2013
(A) Schematic representation of the transgene measuring NHEJ activity. A GFP gene lacking the ATG start codon was cloned out of frame and downstream of an exogenous sequence containing a meganuclease recognition site. (B) Quantification by flow cytometry
Frédéric Pâques (12460), Rachel Macmaster (276589), Fabien Delacôte (276583), George H. Silva (276590), Nathalie Ollivier (276588), Fayza Daboussi (6684), Philippe Duchateau (22729), Marianne Duhamel (276586), Christophe Perez (276584), Christelle Rochon (276587), Valérie Guyot (276585)   +10 more
core   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

Advanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang, Liechao Yu, Wanchang Zhang, Gary Wessel, Ruiyi Chen, Weihua Hu, Dongdong Xu   +6 more
wiley   +1 more source

Análisis de la infraestructura implementada para la TDT en Colombia [PDF]

, 2016
El presente documentó analiza el proceso de implementación de la TDT en Colombia adoptado en el año 2008 a través de la CNTV bajo el estándar DVB-T Europeo y la evolución de la segunda generación DVB-T2 acogida en el año 2011 por el ministerio de las TIC’
José Armando, José Eduar, Becerra Acosta, Gilber, Torres Torres, José Armando   +2 more
core