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Complete Issue Volume 4 Issue 2

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
Editor, Journal of the Scholarship of Teaching and Learning
doaj  

Resolving Artifacts in Voltage‐Clamp Experiments with Computational Modeling: An Application to Fast Sodium Current Recordings

open access: yesAdvanced Science, EarlyView.
Patch‐clamp experiments are fundamental to the measurement and understanding of ion currents that underlie physiological functions from neural activity to muscle contraction. Via a mathematical model of the experimental apparatus, this article highlights how artifact effects can be as large as some reported mutation and drug effects, and enables ...
Chon Lok Lei   +8 more
wiley   +1 more source

Complete Issue Volume 8 Issue 2

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
Editor, Journal of the Scholarship of Teaching and Learning
doaj  

Osteoblast‐CD4+ CTL Crosstalk Mediated by SIRT1/DAAM2 Axis Prevents Age‐Related Bone Loss

open access: yesAdvanced Science, EarlyView.
In the osteoblastic niche, SIRT1 activates and recruits CD4+ CTLs by increasing DAAM2 expression via EZH2 deacetylation and boosting the secretion of key chemokines, such as CCL3, CCL5, and CXCL10. Then, CD4+ CTL directly eliminates senescent osteoblasts in an MHC‐II‐dependent way, thereby slowing down the process of bone ageing and effectively ...
Bin Yang   +20 more
wiley   +1 more source

Complete Issue Volume 3 Issue 2

open access: yesJournal of the Scholarship of Teaching and Learning, 2012
Editor, Journal of the Scholarship of Teaching and Learning
doaj  

Emerging Nanotechnology Strategies for Obesity Therapy

open access: yesAdvanced Science, EarlyView.
Three types of nanomaterials used for obesity treatment are highlighted, including inorganic nanomaterials, organic nanomaterials and biomimetic nanomaterials. A detailed and comprehensive introduction to the recent nanotechnology strategies for obesity management is also provided, including drug delivery, photodynamic therapy, hyperthermia, gas ...
Weili Chang   +5 more
wiley   +1 more source

Volume 15, Number 3

open access: yesJournal of the Scholarship of Teaching and Learning, 2015
Editor Journal of the Scholarship of Teaching and Learning
doaj  

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