Results 51 to 60 of about 7,420,775 (255)

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Factors Influencing Consumer Decisions, Taking into Account Modern Trends and Challenges [PDF]

Problemi Ekonomiki
The article is aimed at determining the modern factors influencing the choice of consumers, consumer decisions, taking into account both the developed approaches and the latest trends and challenges; systematization of factors.
Nikiforov Andrii A., Portna Oksana V.
doaj   +1 more source

Technologies for the Disabled [PDF]

, 2017
Nowadays computers have taken the dominant role in our society.Most jobs now require access to computers and the Internet. But what happens if a person is blind, deaf or physically disabled?
Grechikhina, Julia, Martynenko, A.A., Nechai, N.M.   +2 more
core  

Emerging technologies in physics education [PDF]

, 2007
Three emerging technologies in physics education are evaluated from the interdisciplinary perspective of cognitive science and physics education research.
AB Arons, AS Dhillon, E Mazur, EF Redish, EF Redish, EH Schoenfeld, J Lemke, J Snyder, JH Larkin, K VanLehn, KM Polacek, LS Vygotsky, R Trumper, RD Knight, RK Thornton, S Carey, TA Grotzer, W Christian, WH Leonard, Zosia A. C. Krusberg   +19 more
core   +3 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Who adopts microheating technologies? [PDF]

, 2009
Despite the increasing emphasis on the importance of microgeneration heat, such as solar thermal and biomass stoves, adoption by UK householders has been very slow.
Caird, Sally, Roy, Robin
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Evaluation of Extension Agents Commitment to the Agricultural Loans and Inputs Supply Programme on Special Rice Production in Delta State, Nigeria

Journal of Applied Sciences and Environmental Management, 2014
The study evaluated the activities of Extension agents on Agricultural Loans and Inputs Supply Programme participant farmers’ rice output/income. Data were collected with the aid of questionnaire from 60 Extension agents (participating in the ALIS ...
G F Okwuokenye, D U Okoedo-Okojie
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source