Results 181 to 190 of about 3,270 (204)
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Monitoring Salivary Concentrations of Tedizolid and Linezolid Using Rats
European Journal of Drug Metabolism and Pharmacokinetics, 2023Therapeutic drug monitoring (TDM) is an effective tool for the management of patients who are administered linezolid. The use of saliva for TDM has potential advantages over the use of plasma; however, only a few reports have compared drug concentrations in the saliva and plasma. Moreover, there are no reports on the salivary concentration of tedizolid,
Yuki Inoue +5 more
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Tedizolid (TR-701): a new oxazolidinone with enhanced potency
Expert Opinion on Investigational Drugs, 2012Tedizolid phosphate (TR-701) is a new oxazolidinone prodrug that is transformed in the serum into the active drug tedizolid (TR-700). Tedizolid acts by inhibiting protein synthesis and has broad activity against Gram-positive pathogens, including strains that are resistant to linezolid.This review summarizes the currently available data on this new ...
Zeina A, Kanafani, G Ralph, Corey
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Early Experience with Tedizolid: Clinical Efficacy, Pharmacodynamics, and Resistance
Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2014Antimicrobial resistance among gram‐positive organisms such as methicillin‐resistant Staphylococcus aureus (MRSA) and vancomycin‐resistant enterococci (VRE) continues to limit therapeutic options. The oxazolidinones are a synthetic class of agents now commonly relied on for the treatment of serious MRSA and VRE infections.
Jeffrey M, Rybak +2 more
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Tedizolid for osteoarticular infections: Evaluation of the published evidence
European Journal of PharmacologyTedizolid phosphate, an oxazolidinone antibiotic, has been approved for the treatment of acute bacterial skin and skin structure infections (ABSSSIs). However, its off-label use has been reported in various infections, including osteoarticular infections.A systematic review of data from PubMed, Scopus, and Web of Science was conducted to evaluate the ...
Veatriki Athanasiou +4 more
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Fosfato de tedizolid (antibacteriano) análisis retrosintético II
2022Torres, Hector +1 more
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