Results 141 to 150 of about 47,830 (278)

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Sabine Elisabeth Groeger, Yuxi Zhou, Jiawen Yong, Lei Wang, Sabine Ruf, Joerg Meyle   +5 more
wiley   +1 more source

VanGardeRory seminar presentation 06-15-11.pdf [PDF]

Understanding the mechanisms through which stem cells self-renew is important for the development of new therapies to repair and restore damaged tissue.
VanGarde, Aurora
core  

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Telomere-binding proteins Taz1 and Rap1 regulate DSB repair and suppress gross chromosomal rearrangements in fission yeast. [PDF]

PLoS Genet, 2019
Irie H, Yamamoto I, Tarumoto Y, Tashiro S, Runge KW, Ishikawa F.   +5 more
europepmc   +1 more source

Mapping and Functional Characterization of Homologous Genes AhSUCA06 and AhSUCA16 Underlying Sucrose, Oil and Protein Contents in Peanut (Arachis hypogaea L.)

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng, Feiyan Qi, Lei Shi, Ziqi Sun, Hongfei Liu, Hua Liu, Li Qin, Juan Wang, Chenyang Zhi, Mengmeng Wang, Ziqiang Mo, Stefano Pavan, Xiao Wang, Yaojun Hu, Huanhuan Zhao, Xiaona Li, Wenzhao Dong, Meng Zhang, XiaoDong Dai, Zheng Zheng, Xinyou Zhang   +20 more
wiley   +1 more source

Durum Wheat cv. Svevo Reference Genome Rel.2.0: A Comprehensive Tool for Wheat Genomics

Plant Biotechnology Journal, EarlyView.
ABSTRACT Advancements in plant genome sequencing and assembly have enabled the production of increasingly accurate and contiguous genome sequences. Here, we present the chromosome‐level assembly of the durum wheat (Triticum turgidum L. ssp. durum, cv. Svevo) reference genome produced using accurate long‐reads, optical mapping and Hi‐C. The new assembly
Elisabetta Mazzucotelli, Cristian Forestan, Gina Zastrow‐Hayes, David Swarbreck, Yael Lev‐Mirom, Emile Cavalet‐Giorsa, Matteo Bozzoli, Anna Maria Mastrangelo, Daniela Marone, Vincent Ranwez, Johanna Girodolle, Victor Llaca, Kevin Fengler, Charlotte Harris, Helena Toegelová, Pavla Navrátilová, Primetta Faccioli, Francesca Desiderio, Ana Paola Valladares, Gemy Kaithakottil, Rachel L. Rusholme‐Pilcher, Manuel Spannagl, Heidrun Gundlach, Klaus F. X. Mayer, Victoria C. Blake, Justin D. Faris, Steven S. Xu, Taner Z. Sen, Eric Yao, Julio Isidro y Sánchez, Chunyi Liu, Muhammad A. Farooq, Sandra Stefanelli, Chiara Cappucci, Leah Oren, Tamar Eilam, Mario Giorgioni, Alessandra Stella, Barbara Lazzari, Massimiliano Lauria, Aldo Ceriotti, Raul Pirona, Elahe Tavakol, Valentyna Klymiuk, Jennifer Ens, Harmeet Singh Chawla, Sean Walkowiak, Nicola Pecchioni, Filippo M. Bassi, Miguel Sanchez‐Garcia, Gabriella Sonnante, Pasquale L. Curci, Giovanni Giuliano, Giuseppe Aprea, Asher Pasha, Agata Gadaleta, Ilaria Marcotuli, Stefania Masci, Francesco Sestili, Samuela Palombieri, Davide Scaglione, Michele Morgante, Hana Šimková, Nicholas J. Provart, Simon G. Krattinger, Curtis J. Pozniak, Nathalie Chantret, Anthony Hall, Assaf Distelfeld, Roberto Tuberosa, Marco Maccaferri, Luigi Cattivelli   +71 more
wiley   +1 more source

Identification and characterization of a TRF2-like telomere-binding protein in Arabidopsis

Abstract Telomere protection and maintenance are mediated by proteins that bind telomeric DNA and recruit additional components of telomeric chromatin. While these factors are well characterized in yeast and mammals, their counterparts in plants remain poorly defined. Here, we used a proteomic approach in
Jana Fulneckova, Jana Faturova, Jaroslav Fulnecek, Jana Pecinková, David Potesil, Ganji Sri Ranjani, Zbynek Zdrahal, Karel Riha   +7 more
openaire   +1 more source

High‐Contiguity Haplotype‐Resolved Genome Assembly of the Hexaploid Actinidia valvata Rootstock Sheds Light on Waterlogging Resistance Gene

Plant Biotechnology Journal, EarlyView.
ABSTRACT Polyploidisation, creating redundant or diverged copies of the genome, is a major driving force in plant evolution, diversification and environmental adaptation, including for the kiwifruit genus (Actinidia Lindl.). We present a high‐contiguity, haplotype‐resolved genome assembly of the hexaploid Actinidia valvata rootstock cultivar ...
Miaomiao Lin, Zhi Li, Cecilia H. Deng, Congcong Li, Zhengzhen Zhang, Yukuo Li, Qina Zhang, Peng Zhang, Leiming Sun, Mingyu Liu, Jinbao Fang, Xiujuan Qi   +11 more
wiley   +1 more source

Insights Into the Origin and Local Adaptation Evolution of the Cultivated Sesame With Telomere‐to‐Telomere High‐Quality Genome

Plant Biotechnology Journal, EarlyView.
ABSTRACT Sesame (Sesamum indicum L., 2n = 26) is one of the oldest oilseed crops and is often called the ‘queen of oilseeds’ due to its high content of unsaturated fatty acids and natural antioxidants. Despite its long history, the origin and global spread of cultivated sesame remain unresolved.
Weifei Yang, Hengchun Cao, Hui Guo, Hongmei Miao, Guiting Li, Yinghui Duan, Ming Ju, Qiuzhen Tian, Qin Ma, Pengjie Chang, Zhanyou Zhang, Cong Mu, Xiaoxu Feng, Libin Wei, Weixiu Hou, Andrew H. Paterson, Haiyang Zhang   +16 more
wiley   +1 more source

RAD51 and RAD51 paralog inhibition sensitizes nonreplicating quiescent keratinocytes to UV radiation

Photochemistry and Photobiology, EarlyView.
UV radiation and other compounds generate DNA adducts that block transcription and induce cell death if not removed by the nucleotide excision repair system. In this work, we used a small‐scale pharmacological screen to discover that inhibition of the recombinase RAD51 sensitized nonreplicating quiescent keratinocytes to both UVR and other agents that ...
Saman Khan, Angitha Nair, M. Alexandra Carpenter, Michael G. Kemp   +3 more
wiley   +1 more source