Results 151 to 160 of about 77,771 (318)
Clinical Significance of Telomere Length and Associated Proteins in Oral Cancer
Biomarker Insights, 2007 Purpose: Telomere shortening is an important event during carcinogenesis. Although studies suggest role of multiple proteins in telomere length regulation, there is dearth of reports in oral cancer which is a leading malignancy in Asian countries ...
Rachana N. Sainger +3 more
doaj
Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum
Plant Biotechnology Journal, EarlyView.ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao +6 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang +10 more
wiley +1 more source
Fission yeast telomere-binding protein Taz1 is a functional but not a structural counterpart of human TRF1 and TRF2 [PDF]
, 2015 Wei Deng +7 more
openalex +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Cultivated peanut (Arachis hypogaea L.) is an important oilseed and cash crop, and seed sucrose content (SSC), seed oil content (SOC) and seed protein content (SPC) are key determinants of seed flavour, texture, and overall quality. Identifying quantitative trait loci (QTLs) and candidate genes associated with SSC, SOC and SPC is therefore of ...
Yuzhen Zheng +20 more
wiley +1 more source
Correction: Telomeric Repeats Facilitate CENP-ACnp1 Incorporation via Telomere Binding Proteins
PLoS ONE, 2013 doaj +1 more source
Telomeres stall DNA loop extrusion by condensin
Cell ReportsSummary: DNA loop extrusion by SMC proteins is a key process underlying chromosomal organization. It is unknown how loop extruders interact with telomeres where DNA is densely covered with proteins.
Brian T. Analikwu +14 more
doaj +1 more source
Immune dysregulation in mania: A proof‐of‐concept platelet proteomics study
Psychiatry and Clinical Neurosciences, EarlyView.Aims Bipolar disorder (BD) is a major psychiatric condition with a multifaceted and largely unknown pathophysiology. Mania, the defining feature of BD, remains underinvestigated. Proteomics offers a powerful, data‐driven, unbiased approach to uncover biological alterations.
Paola Magioncalda +6 more
wiley +1 more source
Photochemistry and Photobiology, EarlyView.Exposure to solar ultraviolet radiation is the main etiologic driver of nonmelanoma skin cancers (NMSCs), including basal cell (BCC) and cutaneous squamous cell carcinomas (cSCC), which are the most prevalent types of cancers in the US. In this study, we demonstrate that the serine/threonine kinase Polo‐like kinase 4 (PLK4) is overexpressed in NMSCs ...
Mary A. Ndiaye +5 more
wiley +1 more source