Results 111 to 120 of about 110,933 (294)

The association between alcohol consumption and telomere length: A meta-analysis focusing on observational studies [PDF]

, 2018
Jianqiang Li, Yu Guan, Faheem Akhtar, Xi Xu, Ji-Jiang Yang, Shi Chen, Qing Wang, Hui Pan, Weiliang Qiu   +8 more
openalex   +1 more source

A pilot study of LINE-1 copy number and telomere length with aging in human sperm [PDF]

, 2023
Thalita S. Berteli, Fang Wang, Paula Andrea Navarro, Fabiana B. Kohlrausch, David L. Keefe   +4 more
openalex   +1 more source

The Impact of HIV and Parasite Single Infection and Coinfection on Telomere Length: A Systematic Review

Current Issues in Molecular Biology
HIV and parasite infections accelerate biological aging, resulting in immune senescence, apoptosis and cellular damage. Telomere length is considered to be one of the most effective biomarkers of biological aging.
Engelinah D. Macamo, Zilungile L. Mkhize-Kwitshana, Julian Mthombeni, Pragalathan Naidoo   +3 more
doaj   +1 more source

Reference Intervals for Lymphocyte Subpopulations in Healthy Chinese Han Adults: A Single‐Center Study

Journal of Clinical Laboratory Analysis, EarlyView.
Correlation matrix analysis of lymphocyte parameters. The correlation matrix showed the positive (red) or negative (blue) correlation of two parameters; the color intensity reflected the correlation coefficient. Conducting lymphocyte testing in health management can help monitor immune status, evaluate health risks, analyze pathogenesis of diseases ...
An‐Na Jiang, Lin‐Zi Miao, Yan Gong, Ran You, Yao Lu, Chen‐Xue Qu   +5 more
wiley   +1 more source

A CPC-shelterin-BTR axis regulates mitotic telomere deprotection

Nature Communications
Telomeres prevent ATM activation by sequestering chromosome termini within telomere loops (t-loops). Mitotic arrest promotes telomere linearity and a localized ATM-dependent telomere DNA damage response (DDR) through an unknown mechanism.
Diana Romero-Zamora, Samuel Rogers, Ronnie Ren Jie Low, Scott G. Page, Blake J. E. Lane, Shunya Kosaka, Andrew B. Robinson, Lucy French, Noa Lamm, Fuyuki Ishikawa, Makoto T. Hayashi, Anthony J. Cesare   +11 more
doaj   +1 more source

Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review

Medicine Bulletin, EarlyView.
ABSTRACT Aging is orchestrated by interconnected hallmarks such as genomic instability, mitochondrial dysfunction, cellular senescence, and disrupted intercellular communication, which collectively drive chronic disease progression. Recent advances have expanded therapeutic opportunities to include pharmacological agents, gene and epigenome editing ...
Yundong Peng, Rui Li, Huan Li, Jun Zhou, Xuanshi Liu, Guilherme Valente, Tatiana de Campos Melo, Sifan Chen, Lei Gu   +8 more
wiley   +1 more source

Lennox–Gastaut syndrome in a patient with biallelic TELO2 variants

Epileptic Disorders, EarlyView.
Melissa Odabassian, Kenneth A. Myers
wiley   +1 more source

Coupling CZE, Liquid‐Phase Ion Mobility, to MS/MS for Quantitative Top‐Down Proteomics: Revealing Significant Proteoform Differences Between Healthy and Alzheimer's Disease Brains

PROTEOMICS, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a neurodegenerative disorder characterized by cognitive decline and pathological protein aggregation. Comprehensive quantitative proteomics of brain tissues from AD patients is critical for pursuing a better understanding of the molecular mechanisms that drive AD progression.
Mehrdad Falamarzi Askarani, Fei Fang, Scott E. Counts, Liangliang Sun   +3 more
wiley   +1 more source

Association between modifiable lifestyle factors and telomere length: a univariable and multivariable Mendelian randomization study

Journal of Translational Medicine
Background Telomere length has long been recognized as a valuable biomarker of aging and is inversely correlated with chronological age. Various lifestyle factors have been implicated in telomere shortening or preservation; however, the association ...
Miao Chen, Zhen Wang, Hongfei Xu, Peng Teng, Weidong Li, Liang Ma   +5 more
doaj   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source