Telomere length-variation in deletion strains of Saccharomyces cerevisiae was used to identify genes and pathways that regulate telomere length. We found 72 genes that when deleted confer short telomeres, and 80 genes that confer long telomeres relative ...
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The Role of Telomere in Cell; Telomere Dysfunction and Tumorigenesis
Telomeres consist of repetitive DNA sequences and a variety of non-nucleosomal proteins which are essential to survive chromosome. Telomeres protect the ends of chromosomes, but can also inhibit the expression of nearby genes, called telomere position ...
Majid Kheirollahi +4 more
doaj
Telomere Dynamics in Congenital Heart Defects: Hidden Architects of Cardiogenesis? [PDF]
Joshi R, Nath S, Gupta S.
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Telomere-targeting anticancer drugs
In normal somatic cells, telomere length decreases with each replication event, until a critical state of replicative senescence is reached. On the contrary, telomere maintenance is evident in all types of cancer cells.
PAGANO, BRUNO
core
Age-related cardiac dysfunction is not associated with shorter telomere length in laboratory rats. [PDF]
Strandberg ST +11 more
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Induction of Global Stress Response in Saccharomyces Cerevisiae Cells Lacking Telomerase
Cellular senescence is a major intermediate step from healthy cells toward tumor cells. By using microarrays that simultaneously examine the transcription levels of 6,200 Saccharomyces cerevisiae genes, we show that 45 gene transcript levels are ...
TENG, SHU-CHUN, 鄧述諄
core
Dietary Echinacea purpurea Attenuates Oxidative Stress and Alters Cytokine Gene Expression Among Heat-Stressed Broiler Chickens at High Altitude. [PDF]
Bahadoran S, Vaeznia S, Hassanpour H.
europepmc +1 more source
Kinetic Control of Condensate Function: How the Formation Dynamics of APBs Influence ALT Cancer Telomere Length Heterogeneity. [PDF]
Zhang H.
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Taming Mre11-Rad50 at Telomeres: Convergent Strategies for Chromosome-End Protection Across Evolution. [PDF]
Roisné-Hamelin F, Gruber S.
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MUC5B/TGF-β/KL-6 Signaling in Idiopathic Pulmonary Fibrosis: Genetic Susceptibility to Profibrotic Progression and Clinical Perspectives. [PDF]
Venkatesharao SM, Jayaraman A.
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