Results 111 to 120 of about 130,635 (210)

Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast.

open access: yesPLoS Genetics, 2006
Telomere length-variation in deletion strains of Saccharomyces cerevisiae was used to identify genes and pathways that regulate telomere length. We found 72 genes that when deleted confer short telomeres, and 80 genes that confer long telomeres relative ...
doaj   +1 more source

The Role of Telomere in Cell; Telomere Dysfunction and Tumorigenesis

open access: yesمجله دانشکده پزشکی اصفهان, 2013
Telomeres consist of repetitive DNA sequences and a variety of non-nucleosomal proteins which are essential to survive chromosome. Telomeres protect the ends of chromosomes, but can also inhibit the expression of nearby genes, called telomere position ...
Majid Kheirollahi   +4 more
doaj  

Telomere-targeting anticancer drugs

open access: yes, 2011
In normal somatic cells, telomere length decreases with each replication event, until a critical state of replicative senescence is reached. On the contrary, telomere maintenance is evident in all types of cancer cells.
PAGANO, BRUNO
core  

Age-related cardiac dysfunction is not associated with shorter telomere length in laboratory rats. [PDF]

open access: yesFront Cardiovasc Med
Strandberg ST   +11 more
europepmc   +1 more source

Induction of Global Stress Response in Saccharomyces Cerevisiae Cells Lacking Telomerase

open access: yes, 2009
Cellular senescence is a major intermediate step from healthy cells toward tumor cells. By using microarrays that simultaneously examine the transcription levels of 6,200 Saccharomyces cerevisiae genes, we show that 45 gene transcript levels are ...
TENG, SHU-CHUN, 鄧述諄
core  

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