Results 161 to 170 of about 130,635 (210)

RTEL1 mutation modifies dyskeratosis congenita caused by a telomerase RNA template mutation. [PDF]

Nat Commun
Deimler N, Orioli A, Holthöfer L, Linke M, Bobon N, Engelhardt V, Erichsen L, Paul NW, Meyer R, Beier F, Schweiger S, Baumann P.   +11 more
europepmc   +1 more source

Salivary telomere length in oral leukoplakia and oral squamous cell carcinoma: A preliminary case- control study. [PDF]

J Oral Biol Craniofac Res
Chauhan A, Angadi PV, Kulkarni BB, Belawadi MS, Patil R, Sakthi K.   +5 more
europepmc   +1 more source

Telomere biology disorders in childhood interstitial lung disease: from genetic diagnosis to bedside suspicion - A commentary on "Telomere biology disorders associated with childhood interstitial lung disease". [PDF]

Clin Exp Pediatr
Lilitwat W.
europepmc   +1 more source

Molecular markers, mechanisms and metrics of biological aging: a scoping review. [PDF]

Front Aging
Ziesel A, Reeves J, Mallidou A, Newton L, Rhodes RE, Zhang J, Paterson T, Jabbari H.   +7 more
europepmc   +1 more source

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Telomeres in evolution and evolution of telomeres

Chromosome Research, 2005
This paper examines telomeres from an evolutionary perspective. In the monocot plant order Asparagales two evolutionary switch-points in telomere sequence are known. The first occurred when the Arabidopsis-type telomere was replaced by a telomere based on a repeat motif more typical of vertebrates. The replacement is associated with telomerase activity,
Jirí, Fajkus, Eva, Sýkorová, Andrew R, Leitch   +2 more
openaire   +2 more sources

Telomere telomere recombination provides an express pathway for telomere acquisition

Nature, 1990
DNA termini from Tetrahymena and Oxytricha, which bear C4A2 and C4A4 repeats respectively, can support telomere formation in Saccharomyces cerevisiae by serving as substrates for the addition of yeast telomeric C1-3A repeats. Previously, we showed that linear plasmids with 108 base pairs of C4A4 DNA (YLp108CA) efficiently acquired telomeres, whereas ...
S S, Wang, V A, Zakian
openaire   +2 more sources

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

Nature Reviews Cancer, 2011
Mammalian telomeres are formed by tandem repeats of the TTAGGG sequence, which are progressively lost with each round of cell division. Telomere protection requires a minimal length of TTAGGG repeats to allow the binding of shelterin, which prevents the activation of a DNA damage response (DDR) at chromosome ends.
Paula Mart�nez, Mar�a A. Blasco
openaire   +2 more sources

Telomeres

Experimental Gerontology, 2006
The role that telomere biology may play in the human ageing process is of a significant interest to many laboratories around the world. In this, the first of a series of yearly reviews on telomeres and ageing, I review a small selection of papers published between July 2005 and June 2006 that maybe of direct relevance to the gerontology research ...
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Telomeres

Current Opinion in Cell Biology, 1991
Telomeres are essential for chromosome stability and replication. Maintaining a balance between telomere shortening and lengthening is essential for cell viability. Recent work on telomeres from yeast, Drosophila and mammals, and on telomerase has provided insight into the mechanisms of both the shortening and lengthening processes.
openaire   +2 more sources