Results 171 to 180 of about 116,824 (219)

Lymphoid malignancy and clonality in the POT1-mediated long telomere syndrome.

Blood
Davidson-Swinton HR, Iyer S, Kolchinski A, Salem JA, DeBoy EA, Kilada AG, Hwang JS, Jain T, Keel SB, Gocke CD, Zou YS, Schratz KE, Armanios M.   +12 more
europepmc   +1 more source

Some of the next articles are maybe not open access.

Related searches:

Telomeres in evolution and evolution of telomeres

Chromosome Research, 2005
This paper examines telomeres from an evolutionary perspective. In the monocot plant order Asparagales two evolutionary switch-points in telomere sequence are known. The first occurred when the Arabidopsis-type telomere was replaced by a telomere based on a repeat motif more typical of vertebrates. The replacement is associated with telomerase activity,
Jirí, Fajkus, Eva, Sýkorová, Andrew R, Leitch   +2 more
openaire   +2 more sources

Telomere telomere recombination provides an express pathway for telomere acquisition

Nature, 1990
DNA termini from Tetrahymena and Oxytricha, which bear C4A2 and C4A4 repeats respectively, can support telomere formation in Saccharomyces cerevisiae by serving as substrates for the addition of yeast telomeric C1-3A repeats. Previously, we showed that linear plasmids with 108 base pairs of C4A4 DNA (YLp108CA) efficiently acquired telomeres, whereas ...
S S, Wang, V A, Zakian
openaire   +2 more sources

Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins

Nature Reviews Cancer, 2011
Mammalian telomeres are formed by tandem repeats of the TTAGGG sequence, which are progressively lost with each round of cell division. Telomere protection requires a minimal length of TTAGGG repeats to allow the binding of shelterin, which prevents the activation of a DNA damage response (DDR) at chromosome ends.
Paula Mart�nez, Mar�a A. Blasco
openaire   +2 more sources

Telomere uncapping and alternative lengthening of telomeres

Mechanisms of Ageing and Development, 2008
A substantial number of human tumors utilize a telomerase-independent telomere length maintenance mechanism referred to as alternative lengthening of telomeres (ALT). Although it is known that ALT is a telomere-specific, loss of function phenotype, which involves lengthening of telomeres by homologous recombination-mediated replication of telomeric DNA,
Anthony J, Cesare, Roger R, Reddel
openaire   +2 more sources

Telomeres

Experimental Gerontology, 2006
The role that telomere biology may play in the human ageing process is of a significant interest to many laboratories around the world. In this, the first of a series of yearly reviews on telomeres and ageing, I review a small selection of papers published between July 2005 and June 2006 that maybe of direct relevance to the gerontology research ...
openaire   +2 more sources