Results 131 to 140 of about 57,502 (259)
Abstract Sarcopenia and frailty are complex geriatric syndromes influenced by a combination of genetic and environmental factors. Recent studies suggest that specific genetic variants, DNA methylation patterns and shortened telomeres are associated with age‐related diseases and might contribute to the development of both sarcopenia and frailty. In this
Valentina Ginevičienė +10 more
wiley +1 more source
Early adversity and the comorbidity between metabolic disease and psychopathology
Abstract figure legend Hierarchical diagram representing the interplay between the genetic background and early life adversities and its effect on multiple physiological processes that ultimately impact on the risk for the comorbdity between psychopathology and cardiometabolic disorders.
Ameyalli Gómez‐Ilescas +1 more
wiley +1 more source
Evaluation of the Telomere Length in Patients with Spinal Muscular Atrophy. [PDF]
Okur Altındaş B +3 more
europepmc +1 more source
ABSTRACT SHOX gene haploinsufficiency is associated with Léri‐Weill dyschondrosteosis (LWD) or idiopathic short stature (ISS) and could be caused by the structural and point mutations in the coding region and by the deletions in SHOX gene regulatory sequences. The role of the duplications in regulatory sequences is ambivalent.
Valeriia Kopytko +3 more
wiley +1 more source
Parental Age Effects on Offspring Telomere Length Across Vertebrates: A Meta-Analysis. [PDF]
Vlasova M, Sun Y, Chik HYJ, Dugdale HL.
europepmc +1 more source
Genome Assemblies of the MY73 Parental Lines and Genetic Dissection of Its Superior Performance
Plant Biotechnology Journal, EarlyView.
Haixia Zeng +10 more
wiley +1 more source
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang +7 more
wiley +1 more source
Abstract Stripe rust, caused by Puccinia striiformis f. sp. tritici, is among the most destructive wheat (Triticum aestivum L.) diseases. Identifying resistance genes is crucial for the development of resistant cultivars. Baker's Ann, a hard winter wheat cultivar developed by Oklahoma State University, has shown stable adult plant resistance to stripe ...
Rajat Sharma +10 more
wiley +1 more source

