Results 151 to 160 of about 59,573 (233)

The aging paradox of Cushing's syndrome: Stress without clear senescence?

Journal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Cushing's syndrome (CS), characterized by chronic endogenous hypercortisolism and disruption of the normal circadian cortisol rhythm, represents a unique human model for investigating the interplay between stress endocrinology and biological aging.
Israel Nunes Silveira, Alexandro Guterres   +1 more
wiley   +1 more source

Structure and sequence evolution in the pennycress (Thlaspi arvense) pangenome

New Phytologist, Volume 250, Issue 5, Page 2723-2741, June 2026.
Summary Eukaryotic genomes harbor many forms of variation, including nucleotide diversity and structural polymorphisms, which experience natural selection and contribute to genome evolution and biodiversity. Harnessing this variation for agriculture hinges on our ability to detect, quantify, catalog, and deploy genetic diversity. Here, we explore seven
Kevin A. Bird, Joanna L. Rifkin, Chloee M. McLaughlin, Avril M. Harder, Pawan Basnet, Ella Katz, Tomáš Brůna, Kerrie Barry, LoriBeth Boston, Christopher Daum, Jie Guo, Anna Lipzen, Christopher Plott, Jerry W. Jenkins, Rachel Walstead, Shanmugam Rajasekar, Jayson Talag, Katherine Frels, Kathleen Greenham, Shelby Ellison, Jane Grimwood, Jeremy Schmutz, Patrick P. Edger, J. Chris Pires, John T. Lovell, Daniel J. Kliebenstein   +25 more
wiley   +1 more source

Exposure to Endocrine Disruptors and Stress Hormones Across Pregnancy Trimesters: Links with Maternal Telomere Length. [PDF]

J Xenobiot
Vakonaki E, Hatzidaki E, Baliou S, Marmara M, Alegakis A, Mylonaki E, Volonaki Z, Makrygiannakis F, Tsatsakis A, Tzatzarakis MN.   +9 more
europepmc   +1 more source

PWO proteins are associated with PRC2 since their emergence in vascular plants

New Phytologist, Volume 250, Issue 6, Page 4002-4021, June 2026.
Summary The Polycomb repressive complex 2 (PRC2), a conserved histone methyltransferase complex, plays a central role in transcriptional silencing across eukaryotes. Here, we investigate the evolution of PWWP‐DOMAIN INTERACTORS OF POLYCOMBS (PWOs), which interact with PRC2, and examine the conservation of the PWOs‐PRC2 interaction across plant ...
Ahamed Khan, Saqlain Haider, Abdoallah Sharaf, Alžbeta Kusová, Jan Skalák, Claire Jourdain, Martin Rennie, Petra Procházková Schrumpfová, Jan Hejátko, Daniel Schubert, Sara Farrona, Iva Mozgová   +11 more
wiley   +1 more source

Relative Leukocyte Telomere Length Is Associated with Multimorbidity Burden in Older Adults: Evidence for Sex-Specific Associations. [PDF]

Int J Mol Sci
La Grotta R, Crocco P, Leonova A, Dato S, Passarino G, Rose G.   +5 more
europepmc   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4204-4220, June 2026.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Exploring the synergy between telomere length and genomic complexity in CLL. [PDF]

Br J Haematol
Ramos-Campoy S, Puiggros A, Kamaso J, Parker H, Rigolin GM, Haferlach C, Larráyoz MJ, Collado R, Salgado R, Calasanz MJ, Etter L, Valiente A, Abrisqueta P, Bosch F, Gimeno E, Cuneo A, Nguyen-Khac F, Schoumans J, Strefford JC, Espinet B.   +19 more
europepmc   +1 more source

Multi‐Omics Insights Into Anthraquinone Biosynthesis in Rheum tanguticum

Plant Biotechnology Journal, Volume 24, Issue 6, Page 3953-3968, June 2026.
ABSTRACT Rheum tanguticum is renowned for its medicinal properties, including purgative, anti‐inflammatory and hepatoprotective effects, primarily attributed to anthraquinones (AQs). However, the molecular mechanisms of AQs biosynthesis have largely been hindered by insufficient genomic resources and functional genomics investigations.
Shuo Zhao, Yuan Zong, Tao Wang, Jianan Li, Zengrong Ye, Famei Zhang, Guoying Zhou   +6 more
wiley   +1 more source

Telomere Length Is Determined by Intrinsic Factors and Is Shortened During Drought Years in <i>Gallotia galloti</i>. [PDF]

Ecol Evol
Gilbert E, Power ML, Wolberg A, Megía-Palma R, Žagar A, López-Darias M, Carretero MA, Serén N, Beltran-Alvarez P, Wollenberg Valero KC.   +9 more
europepmc   +1 more source

A Near Telomere‐to‐Telomere Genome of Belamcanda chinensis Provides Insights Into Genome Evolution and the Biosynthesis of Characteristic Isoflavones

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4285-4301, June 2026.
ABSTRACT Belamcanda chinensis is a non‐leguminous medicinal plant rich in bioactive isoflavones; however, the lack of a high‐quality reference genome has limited elucidation of its isoflavone biosynthetic and modification network. Here, we present the first near telomere‐to‐telomere genome assembly of B.
Yuan‐Yuan Wang, Bi‐Huan Chen, Gui‐Sheng Xiang, Yi‐Na Wang, Run Yang, Xiao‐Bo Li, Shi‐Yan Yuan, Yu‐Cheng Zhao, Guang‐Hui Zhang, Min‐Jian Qin, Sheng‐Chao Yang   +10 more
wiley   +1 more source