Results 151 to 160 of about 62,113 (243)

Dermal fibroblasts cultured from aged human skin display a pro‐inflammatory phenotype

Journal of Cell Communication and Signaling, Volume 20, Issue 4, December 2026.
Cell‐Autonomous and Microenvironment‐Driven Changes in Human Skin Dermal Fibroblasts During Aging. Aging induces a cell‐autonomous pro‐inflammatory fibroblast phenotype (independent of the ECM microenvironment), with upregulation of 300 genes primarily associated with cytokine and chemokine pathways (e.g., TNF) and downregulation of 177 genes involved ...
Yilei Cui, Mai Shi, Christal Worthen, Sherilyn Grill, Jayakrishnan Nandakumar, Yi Zhao, Gary J. Fisher   +6 more
wiley   +1 more source

DNA methylation-based estimator of blood telomere length (DNAmTL) outperforms qPCR-based telomere length in reflecting clinical and sociodemographic factors in people with HIV infection. [PDF]

Clin Epigenetics
Esteban-Cantos A, Rodríguez-Centeno J, Montejano R, Cadiñanos J, de Miguel-Buckley R, Gutiérrez-García L, Marcelo-Calvo C, Martínez-Martín P, Bernardino JI, de Gea-Grela A, Díez-Vidal A, Oñoro C, Rodés B, Arribas JR.   +13 more
europepmc   +1 more source

Telomere Length [PDF]

, 2011
openaire   +1 more source

Telomere‐to‐telomere CHM13 reference reveals missing truth variants and improves deep learning‐based variant calling in long‐read sequencing data

Quantitative Biology, Volume 14, Issue 4, December 2026.
Abstract Although long‐read sequencing enables comprehensive genomic analysis, its potential is hindered by its reliance on the incomplete GRCh38 reference genome. GRCh38’s unresolved bases, structural errors, and haplotype mosaics introduce reference biases, leading to missed variants and false‐positive calls.
Zhenxian Zheng, Minggao He, Xian Yu, Lei Chen, Junzhe Li, Jingcheng Zhang, Ruibang Luo   +6 more
wiley   +1 more source

From Prevention to Healthy Longevity: Evaluating the Multi‐Systemic Effects of Physical Activity and Lifestyle Behaviours in Women

Reproductive, Female and Child Health, Volume 5, Issue 4, December 2026.
ABSTRACT Purpose Despite spending more on healthcare than any other high‐income nation, the United States faces comparatively poor life expectancy outcomes, primarily due to non‐compliance with preventable and modifiable lifestyle behaviours. This review evaluates the multi‐systemic benefits of physical activity, exercise, diet, weight management and ...
Darah Dilmaghani, Mary Collins, Gloria A. Bachmann   +2 more
wiley   +1 more source

Detection of Longer Leukocyte Telomere Length in Patients With Bone Sarcomas. [PDF]

World J Oncol
Chantre-Justino M, Silvestre RT, Delmonico L, Alves G, Ornellas MHF, Rotilho C, Cavalcanti A, Perini JA, Bastos NC, Luz E, Pinheiro R, Delocco BC, Caruso AC, de Sa Lopes AC, Meohas W.   +14 more
europepmc   +1 more source

Genome evolution of Mediterranean olives following DNA repeats diversification

The Plant Genome, Volume 19, Issue 4, December 2026.
Abstract The olive tree (Olea europaea L. subsp. europaea) is one of the most representative perennial crops of the Mediterranean Basin, yet the genomic processes underlying its domestication and diversification remain poorly understood. Here, we investigated repeatome variation across 20 accessions, including 11 wild oleasters and nine cultivated ...
Flavia Mascagni, Samuel Simoni, Gabriele Usai, Alexis Ryo, Marco Castellacci, Ugo Rogo, Marilena Ceccarelli, Luciana Baldoni, Tommaso Giordani, Lucia Natali, Andrea Cavallini, Guillaume Besnard   +11 more
wiley   +1 more source

Quantifying telomere length: from bulk assays to single-molecule resolution. [PDF]

Biophys Rep
Ma K, Yu Z.
europepmc   +1 more source

New perspectives on the physiological basis of muscle loss

Experimental Physiology, EarlyView.
Alistair J. Monteyne, Marlou L. Dirks
wiley   +1 more source

A Role for Janus Cyclohexyl Ring Motifs in Medicinal Chemistry. Incorporation Into G‐Quadruplex Ligands and Anti‐Trypanosoma brucei Activity

ChemBioChem, Volume 27, Issue 21, 12 November 2026.
Naphthalene diimide (NDI) cores with peripheral fluorocyclohexyl ring systems are explored binding to G‐quadruplex DNA and were also assayed against the Trypanosoma brucei parasite. The most active compound of the series displayed nanomolar activity and suggested electrostatic interactions between the polarized cyclohexane and G‐Quad DNA.
Josephine M. Stewart, Mario Kehler, Vytautas Kuodis, Gary N. Parkinson, Wenqian Chen, Terry K. Smith, Zoë A. E. Waller, David O’Hagan   +7 more
wiley   +1 more source