Results 131 to 140 of about 62,113 (243)

Age-related cardiac dysfunction is not associated with shorter telomere length in laboratory rats. [PDF]

Front Cardiovasc Med
Strandberg ST, Opstad TB, Romaine A, Espe E, Sadredini M, Løken KG, Palmero S, Gravning JA, Sjaastad I, Lunde IG, Stokke MK, Helseth R.   +11 more
europepmc   +1 more source

Cardiometabolic Complications in Pregnancy and Biological Ageing in the Offspring: A Systematic Review and Meta‐Analysis

Paediatric and Perinatal Epidemiology, EarlyView.
ABSTRACT Background Cardiometabolic complications in pregnancy may alter the intrauterine environment, influence offspring biological ageing and potentially increase the risk of chronic diseases later in life. Objectives This systematic review and meta‐analysis aimed to examine associations between diabetes in pregnancy, hypertensive disorders of ...
Eskedar Getie Mekonnen, Tina Bianco‐Miotto, Kai Liu, Jessica A. Grieger   +3 more
wiley   +1 more source

Environmental and Genetic Determinants of Early-Life Telomere Length in Tree Swallows. [PDF]

Mol Ecol
Langlois CA, Pelletier F, Houle C, Martin JGA, Garant D.   +4 more
europepmc   +1 more source

Bone biology in aging periodontal and peri‐implant tissues

Periodontology 2000, EarlyView.
Abstract Background Periodontal disease is an age‐related chronic inflammatory condition leading to tooth loss. Dental implants are an option for replacement of lost teeth in older adults. However, age‐related changes to alveolar bone may have pathological implications for its role in supporting the dentition and dental implants.
Dalia Rasheed Issa, Giuseppe Intini, Daniel Clark   +2 more
wiley   +1 more source

Telomere length of both parents contributes to heritable POT1 cancer-predisposition syndrome. [PDF]

Nat Commun
Martin A, Lu R, Blake A, Nichols KE, Sanchez SE, Artandi SE, Savage SA, Sharma R, Hockemeyer D.   +8 more
europepmc   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Performance of age-adjusted whole genome sequencing telomere length in idiopathic pulmonary fibrosis. [PDF]

Am J Respir Crit Care Med
Kim JS, Receveur B, Zhang D, Ma SF, Huang Y, McGroder C, Putman RK, Podolanczuk AJ, Rotter JI, Rich SS, Flaherty KR, Lee JS, Lasky JA, Raghu G, Murray S, Spino C, Martinez FJ, Oh A, Lynch DA, Humphries SM, Adegunsoye A, Oldham JM, Hunninghake GM, Garcia CK, Taub M, Mathias RA, Cho MH, Barr RG, Noth I, Mychaleckyj JC, Manichaikul A, Newton CA.   +31 more
europepmc   +1 more source

THE ACTIVITY OF TELOMERE LENGTH MAINTENANCE MECHANISMS AND THE TELOMERE LENGTH DYNAMICS

The dataset contains the TCGA  R Scripts and Processed Data for Pan-Cancer and Glioma Telomere Maintenance Analysis. The dataset is organized as follows: ALT_TEL_ATRX_TERT_mutations: folder provides mutation datasets for ALT and TEL pathways, with a focus on ATRX and TERT gene alterations.
openaire   +2 more sources

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Telomere length in patients with non-functional adrenal incidentalomas. [PDF]

Endocr J
Ozdemir N, Ozcan SS, Turkmen AE, Guney SC, Hekimsoy Z, Korkmaz M.   +5 more
europepmc   +1 more source