Results 141 to 150 of about 59,573 (233)

Highly heterozygous Citrus changshan‐huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue‐specific allelic imbalance

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng   +14 more
wiley   +1 more source

iLDA‐SGCN: Identifying Associations Between Age‐Related Diseases and Long Non‐Coding RNAs Using Dual Graph Convolutional Networks

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
iLDA‐SGCN integrates singular value decomposition and dual graph convolutional networks to predict lncRNA‐disease associations. It achieves superior performance on two benchmark datasets and identifies 33 candidate lncRNAs across 8 age‐related diseases.
Yu Guo   +8 more
wiley   +1 more source

Urate‐Related Genetic Risk Modulates the Anti‐Aging Effects of Exogenous Nucleotides: Multi‐Omics Evidence From Older Adults

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
In the TALENTs trial, 19‐week exogenous nucleotide supplementation produced UA‐PRS‐dependent anti‐aging responses: reduced DNA methylation age in High‐PRS individuals and preserved telomere length with improved immune–inflammatory profiles in Low‐PRS individuals, supporting precision nutrition for healthy aging.
Ruisheng Fu   +6 more
wiley   +1 more source

Genomic, phenomic and geographic associations of leukocyte telomere length in the United States. [PDF]

open access: yesNat Genet
Nakao T   +15 more
europepmc   +1 more source

Late Onset Telomere Biology Disorder Presenting With Pancytopenia, Immune Dysregulation, Interstitial Lung Disease and Alopecia

open access: yes
American Journal of Hematology, Volume 101, Issue 6, Page 1196-1200, June 2026.
Bo A. Wan   +7 more
wiley   +1 more source

Dual PARP/Tankyrase Inhibition Enhances Antitumor Efficacy in PTEN‐Deficient Endometrial Cancer

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 11, -Not available-.
ABSTRACT Endometrial cancer (EC) incidence continues to rise, underscoring the need for effective therapies beyond BRCA‐mutant disease. Although PTEN loss, a frequent alteration in EC, has been implicated in impaired homologous recombination and increased sensitivity to PARP inhibitors, responses to PARP inhibitor monotherapy remain variable and are ...
Sung Wan Kang   +6 more
wiley   +1 more source

Neuroendocrine tumours through an epigenetic lens: Emerging insights for diagnosis and treatment

open access: yesJournal of Neuroendocrinology, Volume 38, Issue 6, June 2026.
Abstract Neuroendocrine tumours (NETs) are well‐differentiated epithelial neuroendocrine neoplasms that frequently develop in the small intestine, pancreas, and lungs. NETs originate from neuroendocrine cells specialized in hormone secretion implicated in a number of physiological processes.
Victoria Jacquot   +4 more
wiley   +1 more source

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