Results 151 to 160 of about 45,980 (243)

Endoscopic Ultrasound for the Management of Pancreatic Neuroendocrine Tumors: Diagnosis, Treatment, and Future Perspectives

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Pancreatic neuroendocrine tumors (PanNETs) are increasingly diagnosed, reflecting greater clinical awareness, improved imaging, and revised classification. This review summarizes evidence on epidemiology, diagnostic workup, and endoscopic ultrasound (EUS)–guided management of PanNETs, encompassing diagnostic evaluation, tissue acquisition, and
Angelo Bruni, David Meacci, Roberto Falbo, Marco Fichera, Francesco Poggioli, Riccardo Casadei, Claudio Ricci, Leonardo Henry Eusebi   +7 more
wiley   +1 more source

NPM1 phosphorylation-mediated telomere maintenance via stabilization of POLD3 in ALT-positive osteosarcoma: unraveling mechanisms and therapeutic opportunities. [PDF]

Theranostics
Zhao R, Li T, Yang Q, Jiang D, Xue Y, Kou H, Wang Q, Wang Y, Han X, Ma W, Wang G, Feng J, Han X, Liu Y, Jing Y, Geng X, Wang F, Liu Y, Zhang Q, Wang F.   +19 more
europepmc   +1 more source

Dissecting the genetic basis of climatic adaptation in wild relatives (Malus baccata) for climate‐resilient apple breeding

Journal of Integrative Plant Biology, EarlyView.
This comprehensive map of genetic variation in wild apple (Malus baccata) and set of key genes associated with adaptation to temperature, precipitation, and soil properties establishes a foundation for breeding climate‐resilient apple cultivars and conserving the genetic resources of wild crop relatives.
Ying Su, Yani Hao, Xuejing Cao, Lin Wang, Zhiqi Xu, Fan Zhang, Zhiyao Ma, Xu Wang, Jiacui Li, Tianrong Fan, Ruoyan Zhao, Zhongqi Liu, Wenrui Wang, Yingchun Zhang, Xuanwen Yang, Sifan Yang, Dajiang Wang, Kun Wang, Simiao Sun, Zichen Li, Wen Tian, Yanming Sun, Zhao Liu, Yanshuai Xu, Hua Xiao, Yanling Peng, Xiaodong Xu, Ruirui Liu, Xinmin Tian, Yongfeng Zhou, Yuan Gao   +30 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Is Telomere Length Optimized in Hatchling Sand Lizards? [PDF]

Evol Dev
Olsson M, Miller E, Rollings N, Wapstra E, Shine R.   +4 more
europepmc   +1 more source

The annotated blueprint: integrated functional genomic resources for a model tetraploid wheat Triticum turgidum cv Kronos

New Phytologist, EarlyView.
Summary Triticum turgidum cv Kronos is a tetraploid wheat cultivar that underpins one of the most widely used community platforms for functional genomics. Over the past decade, researchers have generated c. 3000 exome‐capture (EC) and promoter‐capture (PC) datasets linked to mutagenized seed stocks, along with extensive transcriptomic and phenotypic ...
Kyungyong Seong, Rakesh Kumar, Daniil M. Prigozhin, China Lunde, Thales Henrique Cherubino Ribeiro, Sébastien Bélanger, Jo‐Wei Allison Hsieh, McCree Tang, Blake C. Meyers, Ksenia V. Krasileva   +9 more
wiley   +1 more source

Three-Dimensional Organization of Telomeres: An Emerging Prognostic Biomarker in Multiple Myeloma. [PDF]

Cells
Shifrin Y, Mai S.
europepmc   +1 more source

Recombination suppression in plant adaptation and speciation

New Phytologist, EarlyView.
Summary Recombination suppression is increasingly recognized as an important facilitator of genomic divergence and speciation, especially under ongoing gene flow. In plants, however, the broader evolutionary consequences and the mechanisms by which recombination suppression arises and spreads are still incompletely understood, reflecting the inherent ...
Xu Zhang, Yisi Hu, Kaichi Huang, Stephen I. Wright, Loren H. Rieseberg   +4 more
wiley   +1 more source

Molecular Mechanisms of Accelerated Ageing in Geriatric Depression: Interplay of Telomere Attrition, Mitochondrial Dysfunction and Cellular Senescence. [PDF]

Int J Mol Sci
Revi Shanker P, Dorajoo R.
europepmc   +1 more source

Structural Variations Contribute to Subspeciation and Yield Heterosis in Rice

Plant Biotechnology Journal, EarlyView.
ABSTRACT Yield heterosis has been extensively exploited in hybrid breeding, with intersubspecific hybrids often exhibiting the most pronounced effects. However, developing elite hybrids remains a laborious and time‐consuming process. The genetic basis of heterosis has been debated for over a century, hindered largely by the lack of high‐quality genomes.
Zhiwu Dan, Yunping Chen, Wenchao Huang
wiley   +1 more source