Results 181 to 190 of about 59,567 (314)

Centromeres and telomeres as rheological probes of the human cell nucleus. [PDF]

Biophys J
Clavijo AS, Ionov S, Zidovska A.
europepmc   +1 more source

To Treat or Not to Treat: Navigating Early‐Stage CLL in the Era of Targeted Therapy

European Journal of Haematology, EarlyView.
ABSTRACT Chronic lymphocytic leukemia (CLL) is most frequently diagnosed at early, asymptomatic stages (Rai 0/Binet A), in which a watch‐and‐wait strategy remains the standard of care, based on historical trials demonstrating no overall survival benefit from early treatment.
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Giovanna Cutrona, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Franco Fais, Antonino Neri, Manlio Ferrarini, Valter Gattei, Fortunato Morabito, Massimo Gentile   +16 more
wiley   +1 more source

Telomere length dynamics in adults living with HIV: A systematic review. [PDF]

BMC Infect Dis
Massamba MKY, Madurai L, Archary D, Mahomed S.   +3 more
europepmc   +1 more source

Proteostasis of organelles in aging and disease

The FEBS Journal, EarlyView.
Cells rely on regulated proteostasis mechanisms to keep their internal compartments functioning properly. When these mechanisms fail, damaged proteins accumulate, disrupting organelles, such as the nucleus, mitochondria, endoplasmic reticulum, Golgi, and lysosomes, as well as membraneless organelles, such as stress granules, processing bodies, the ...
Yara Nabawi, Cansu Doğan, Dunja Petrović, Gülce Perçin, Seda Koyuncu, David Vilchez   +5 more
wiley   +1 more source

Telomere Length in Metabolic Syndrome: Mechanisms, Epidemiology and Clinical Implications: A Narrative Review. [PDF]

Diabetes Metab Syndr Obes
Cilia K, Gauci Z, Agius R, Fava S, Pace NP.   +4 more
europepmc   +1 more source

Recent advances of emergent extraction technologies to enhance bioactive compounds extraction of microalgae—An overview towards application in cosmetics

International Journal of Cosmetic Science, EarlyView.
Microalgae extracts show immense potential in cosmetics for their bioactivities; emerging extraction techniques enhance bioactive compound yield from microalgae. Abstract Microalgae have attracted significant interest in numerous sectors, particularly in the cosmetic industries, owing to their rich composition of bioactive compounds. This paper aims to
Alireza Mousakhani Ganjeh, Lucília da P. da Silva, Carlos A. Pinto, Rosário Martins, Alexandra P. Marques, Jorge A. Saraiva   +5 more
wiley   +1 more source

Human Telomeres and Recombination

, 2013
Telomeres are DNA-protein complexes that help protecting the end of linear chromosomes. They consist of repetitive DNA, in mammals the repeat unit is the hexanucleotide TTAGGG, these repeats span 5-20 kb.
Alberto Hidalgo Bravo (7641299)
core  

Both genome instability and replicative senescence stem from the shortest telomere in telomerase-negative cells. [PDF]

Nat Commun
Berardi P, Martinez-Fernandez V, Rat A, Rosas Bringas FR, Jolivet P, Langston R, Mattarocci S, Maes A, Aspert T, Zeinoun B, Casier K, Kazemier HG, Charvin G, Doumic M, Chang M, Teixeira MT.   +15 more
europepmc   +1 more source

Inflammation‐Regeneration Axis of Dental Pulp Stem Cells: Wnt/NF‐κB Crosstalk

International Endodontic Journal, EarlyView.
ABSTRACT Background Inflammation critically determines dental pulp regenerative outcomes, with dental pulp stem cells (DPSCs) orchestrating tissue homeostasis through differentiation, self‐renewal and immunomodulation processes dynamically regulated by Wnt/β‐catenin and NF‐κB signaling crosstalk.
V. Rajasekar, M. Huang, M. M. Abdalla, P. Neelakantan, C. K. Y. Yiu   +4 more
wiley   +1 more source

Telomere Length Is Determined by Intrinsic Factors and Is Shortened During Drought Years in <i>Gallotia galloti</i>. [PDF]

Ecol Evol
Gilbert E, Power ML, Wolberg A, Megía-Palma R, Žagar A, López-Darias M, Carretero MA, Serén N, Beltran-Alvarez P, Wollenberg Valero KC.   +9 more
europepmc   +1 more source