Results 191 to 200 of about 66,266 (300)

Metaplasia and the Origins of Gastric Cancer—Implications for Screening and Surveillance

open access: yesJournal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Gastric intestinal metaplasia (IM) is a key step in the development of intestinal‐type gastric cancer (GC) and a checkpoint for preventive strategies. The risk of progression to GC is highest for incomplete IM and extensive severe IM as classified by scoring systems such as operative link on gastric intestinal metaplasia (OLGIM) assessment ...
Khay Guan Yeoh
wiley   +1 more source

Recent advances in the genomics of sugarcane (Saccharum)

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review systematically summarizes advances in sugarcane genomics, evolution, classification, and breeding practices. It identifies key research bottlenecks and proposes an integrated research framework to facilitate predictive sugarcane breeding, which provides valuable references for genetic improvement of other complex polyploid crops.
Tianyou Wang   +5 more
wiley   +1 more source

Plant cis‐regulatory grammar: Decoding the multidimensional code of transcriptional regulation for programmable crop engineering

open access: yesJournal of Integrative Plant Biology, EarlyView.
This review decodes the grammar of plant cis‐regulatory elements, revealing that their function emerges from sequence, chromatin accessibility, 3D topology, and cell type context. It highlights how single‐cell omics, CRISPR dissection, and AI‐driven design converge to enable predictive engineering and crop improvement. ABSTRACT Cis‐regulatory elements (
Libin Zhang, Maoteng Li
wiley   +1 more source

T2T genome assembly and CRISPR/Cas9 editing of Medicago lupulina

open access: yesJournal of Integrative Plant Biology, EarlyView.
A complete, gap‐free genome of Medicago lupulina, a tough, high‐protein forage legume, and a gene‐editing tool for this species, which was used to alter its leaf shape, provide key resources for improving alfalfa and breeding better forage crops for high‐altitude environments.
Qing Yuan   +9 more
wiley   +1 more source

Genome‐scale insights into metabolic streamlining and photosynthetic energy balance in the extremophile green alga Picocystis salinarum (Picocystophyceae, Chlorophyta)

open access: yesJournal of Phycology, EarlyView.
Abstract Picocystis salinarum is an early‐diverging chlorophyte and the sole described member of the Picocystophyceae, frequently dominating hypersaline and alkaline lakes despite extreme physicochemical constraints. To elucidate the genomic foundations of its ecological success, we generated a fully annotated, chromosome‐scale nuclear genome assembly ...
Claude Lemieux   +2 more
wiley   +1 more source

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